RESUMO
Wnt signaling pathway can regulate the proliferation and differentiation of neural stem cells, the growth and develop¬ment of neural cells, which is closely related to the therapeutic mechanism of cerebral ischemia-reperfusion injury (CIRI) after ischemic stroke.Researches have showed that some single Chi¬nese medical herb and Chinese medical herb compounds with the effects of tonifying Shen and nourishing Gan, supplementing Qi and nourishing Yin, promoting Xue and Qi, removing blood sta¬sis and resolving phlegm can activate the Wnt signaling pathway in brains and play the role of treating CIRI, and the essence of the treatment is according to the pathogenesis of CIHI which can be reduced by Yin deficiency of Gan and Shen, Qi and Xue de¬ficiency, blood stasis and phlegm toxin.This paper has summa¬rized the research results of Lycium chinensis, Cornus officinalis, turmeric, Salvia miltiorrhiza and other single Chinese medical herbs and Traditional Chinese Medicine(TCM) compounds such as Naoluoxintong, Danlong Xingnao formula, Yiqi Huoxue For¬mula, Bush en Shengsui formula and Huangjing pill in the treat¬ment of CIHI, regulating Wnt signaling pathway in brains.We also have analyzed that the essence of modern medicine of tonify-ing Shen and producing Sui, supplementing Qi and filling Jing in TCM is closely related to promoting cerebral angiogenesis and re¬modeling and stimulating the proliferation and differentiation of neural stem cells in specific areas of the brain after activating Wnt signaling pathway, and promoting blood circulation and re¬moving blood stasis, resolving phlegm and clearing toxin are re-lated to improving brain blood supply, anti-inflammatory, anti- free radical an ti ox id at ion and other functions.
RESUMO
The effects of prescriptions of fragrant traditional Chinese medicine covered in ancient books on traditional Chinese medicine published in the past dynasties on disease control and treatment were retrieved from the Full-text Database of Ancient Books on Traditional Chinese Medicine developed by Nanjing University of Traditional Chinese Medicine. A fragrant medicinal subject system with unique characteristics was established by analyzing the characteristics of prescribed fragrant traditional Chi-nese medicine and the prescribing rules of fragrant traditional Chinese medicine according to theirprinciples-methods-formulae-medicinal, clarifying the related factors influencing diseases and the related mechanisms of prescriptions, which can not only promote the theoretical and practical development of external treatment with prescriptions of fragrant traditional Chinese medicine but also provide the reliable philological basis for external diseases and pharmacology of traditional Chinese medical formulae.
RESUMO
Objective To reveal the literature resources in traditional Chinese medicine from the end of the Qing Dynasty to 1949 .Methods The papers published in journals of traditional Chinese medicine from the end of the Qing Dynasty to 1949 were statistically analyzed .Results The largest number of journals was published in Shang-hai, the largest number of papers was published in Guanghua Medical Journal, 95%of the papers were published by a single author, the contents were focused on classical prescriptions and proved recipes, food therapy, disease treatment, baby care knowledge, and the most commonly studied were infectious diseases, such as exogenous febrile disease, cholera, and malaria.Conclusion The papers published in journals of traditional Chinese medicine from the end of the Qing Dynasty to 1949 are focused much more on the application of the knowledge about traditional Chinese medicine , but less on the theories of traditional Chinese medicine .