RESUMO
Omega-3 and Omega-6 fatty acids affect growth vitality and mental state. They favorably affect atheroscieorosis, coronary heart diseases, inflammatory diseases and perhaps even behavioral disorders. The aim of the present study was to elucidate the possible effect of feeding rats a diet enriched with 5% of each flaxseed oil or sun flower oil [for 10 weeks]on the levels of brain monoamines and on the parameters of two behavioral tests[open field and swimming tests].90 male rats pups after weaning[21 days of age]were divided into 3 groups: group[1]control untreated, group [2] and [3] subjected to a diet containing [5% flaxseed oil or sun flower oil] respectively for 10 weeks. The results showed that both Omega-3 and 6 produced a significant increase in the levels of serotonin and dopamine. In the open field test omega-3 and omega-6 oils induced a significant increase in the grooming number whereas, induced a significant decrease in the rearing number. Application of swimming test to tested groups revealed that both Omega-3 and Omega-6 induced a significant decrease in latency time, The data showed that both Omega-3 and Omega-6 containing oils cause alterations In the brain functions and behavior in rats
Assuntos
Masculino , Animais de Laboratório , Ácidos Graxos Ômega-6/administração & dosagem , Ácidos Graxos Ômega-3/efeitos adversos , Ácidos Graxos Ômega-6/efeitos adversos , Comportamento Animal , Ratos , Masculino , Serotonina/sangue , Dopamina/sangueRESUMO
Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) are forerunners of type 2 diabetes mellitus (DM) and are now recognised as prediabetes states. Cardiovascular disease (CVD) is associated with these conditions and there are many studies such as the Da Quin IGT and DM study; Finnish Diabetes Prevention Study(DPS); The Diabetes Prevention Program(DPP) which have clearly shown the efficacy and supremacy of diet intervention in controlling progression of the prediabetes state to type 2 DM. Weight reduction, increasing physical activity and restricting not only total calories but also deriving them from more healthy sources by reducing the total intake of fat, changing n-6 PUFA to n-3 PUFA, increasing the intake of fibre rich carbohydrates and the use of antioxidants have not only long-term health benefits but also can be a very useful cost-effective tool to overcome the burden of type 2 DM in our country. Prevention of type 2 DM is not a dream but a reality and this can be achieved from a path through our kitchen. Faulty nutrition seems to be the main culprit in this wide-spread epidemic of diabetes and nutritional therapy in prediabetes state appears to be the only option in our hands.