Apis mellificaem tratamento de urticária crônica e angioedema: relato de caso / Apis mellifica treatment of chronic urticaria and angioedema: case report

É relatado um caso de paciente com quadro de urticária crônica e angioedema com mais de 18 anos de evolução. Mal controle de sintomas com tratamento convencional e visitas cada vez mais frequentes ao pronto socorro deterioravam sua qualidade de vida e traziam insegurança devido ao potencial de gravidade do quadro. Em sua primeira consulta homeopática foi verificado alto grau de semelhança sintomática com a patogenesia de Apis mellifica, o qual foi introduzido e modificou a história de vida da paciente em questão, com excelente controle do quadro clínico. Foi realizada revisão da literatura sobre urticária e o policresto Apis mellifica. Este relato tem como objetivos chamar atenção para a existência e importância de recursos terapêuticos não convencionais, como é o caso da homeopatia, e também compartilhar com os colegas homeopatas a condução do caso, desde o diagnóstico e escolha do medicamento, ao seguimento da paciente.

We report the case of a patient with chronic urticaria and angioedema for more than 18 years. The symptoms were poorly checked with conventional treatment and increasingly frequent visits to the emergency department seriously affected the patient’s quality of life, in addition to making her feel insecure about the severity of her condition. During the first homeopathic consultation we detected a high degree of similarity with the pathogenetic symptoms of Apis mellifica. The remedy was prescribed and changed the patient’s life history, achieving excellent control of her clinical condition. A literature review was performed on urticaria and polycrest medicine Apis mellifica. The aim of this case report is to call the attention to the availability and relevance of non-conventional therapeutic resources, such as homeopathy, and to share with colleagues aspects of the case management from diagnosis and medicine selection to follow up.

Efeito benéfico da propólis sobre a hipercolesterolemia experimental em coelhos / Benefical effects of propolis on experimental hypercholesterolaemia in rabbits

Propolis (bee glue) is one of the major bee hive products and is rich in flavonoids, which are known for their antioxidant effect. To investigate the possible mechanism of propolis therapeutic action, rabbits were distributed into 4 groups (n=6): GI – control; GII – atherogenic diet; GIII – atherogenic diet and ethanol; GIV – atherogenic diet and ethanolic extracts of propolis (EEP=100mg/kg, day). Atherogenic diet (0.14g cholesterol, daily) induced hyperlipidemia in rabbits (male, body weight 2.500?2g) with significant increase of levels of total cholesterol, low density lipoprotein, very low density lipoprotein and triacylglycerol. Treatment with EEP, for 56 days, significantly reduced the levels of these biochemical parameters. The activities of plasma aspartate aminotransferase, alanine aminotransferase and creatine phosphokinase were increased (p<0.05) by atherogenic diet and these increases were largely inhibited by EEP, whereas the adminitration of EEP produced a marked increase in the levels of high density lipoprotein. Treatment of rabbits with EEP resulted in a decrease of hepatic levels of triglycerides, triacylglycerol and total cholesterol. These results suggest that EEP exerts a hypocholesterolaemic effect in high-cholesterol-fed rabbits, and possesses a protective action against the acute hepatic toxicity caused by administration of atherogenic diet