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Egyptian Journal of Chemistry. 2007; 50 (6): 783-794
em Inglês | IMEMR | ID: emr-112276

RESUMO

Some new heterocycles bearing acenaphtho [l,2-e][1,2,4] triazine moiety were synthesized via condensation of N-[acnaphtho[l,2-e][l,2,4]triazin-9-yl] formamide [2] with nitrogen and oxygen reagents. Structural assignment of the synthesized products 2-16 were confirmed by elemental analyses and [1]H-NMR and [13]C-NMR determinations. Screening for some selected compounds showed remarkable anticancer activity


Assuntos
Acenaftenos/síntese química , Antineoplásicos , Anticarcinógenos
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