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Rev. méd. Chile ; 141(8): 1041-1048, ago. 2013. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-698703

RESUMO

For years the mainstay of antiphospholipid syndrome treatment has been anticoagulation and antiplatelet therapy, but the autoimmune nature of the disease, and complications of these therapies, created the need to develop new therapeutic strategies. New therapeutic alternatives inhibit at different levels, the cascade of events leading to the pro-thrombotic state characteristic of the antiphospholipid syndrome. We conducted a literature review of these new treatments, focusing on the pathophysiological bases that support them and their possible clinical applications.


Assuntos
Humanos , Síndrome Antifosfolipídica/tratamento farmacológico , Agmatina/análogos & derivados , Agmatina/uso terapêutico , Anticorpos Monoclonais Murinos/uso terapêutico , Síndrome Antifosfolipídica/fisiopatologia , Dipeptídeos/uso terapêutico , Glucocorticoides/uso terapêutico , Hidroxicloroquina/uso terapêutico , Inibidores de Hidroximetilglutaril-CoA Redutases/uso terapêutico , Trombose/tratamento farmacológico
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