RESUMO
To document whether the varying concentration of epinephrine [in Xylesterin-A and Lidocaton] present in local anesthesia effect the blood pressure and pulse rate. Design: Non-Randomized Experimental Study Design. Design: Non-Randomized Exp. S.D. Setting: Department of Oral Surgery, Karachi Medical And Dental College. Patients and Forty cases were registered. Half of them were given Xylesterin-A [with 1: 115,000] as a local anesthesia during tooth extraction and were labeled as group 1. Rest of the half was given Lidocaton [with 1:80,000 epinephrine] as a local anesthesia and was labeled as group 2. Blood pressure and pulse rate of all the patients was recorded. The Students-T test showed that the varying concentration of epinephrine present in local anesthesia did not affect the blood pressure and pulse rate significantly. Whatever fluctuation occurred was attributed to patients' stress due to -sympathetic overactivity. Epinephrine has a non-significant role in affecting the blood pressure and pulse rate during tooth extraction. Continuous reassurance has a vital role in keeping the blood pressure and pulse rate under control