Results of Photopatch and Patch Tests in 35 Korean Patients with Chronic Actinic Dermatitis and Clinical Importance of These Findings / 대한피부과학회지

BACKGROUND: Chronic actinic dermatitis (CAD) is a rare disease worldwide. It has been defined on the basis of three criteria: 1) clinical - a persistent eczematous eruption on sun- exposed area with possible extension into non-exposed areas, 2) photobiological - a reduction in the minimal erythema dose to UVB irradiation, and possibly longer wavelengths, and 3) histologic - an appearance consistent with chronic eczema, with or without the presence of lymphoma-like changes. However, only a few clinicohistopathologic and photobiological analyses of CAD have been undertaken in Korea. OBJECTIVE: To explore photoallergens and/or allergens causing or thought to be associated with CAD in Korean patients, and to compare the photopatch or patch test results in Korea with those from other countries. METHODS: Thirty-five Korean patients with CAD were enrolled for this study. Photopatch tests were carried out by applying two sets of the Scandinavian photopatch series to each patient. Two days after application, the photopatch tests were analysed, and one set of the photoallergens was irradiated with 50% of the MED-UVA. Both sets of photoallergens were examined 2 days later. A European standard series was used to assess the patch tests. At two and four days after application, patch tests were analysed. RESULT: Twenty-seven of the 35 patients (77.1%) who had photopatch tests showed positive responses; balsam of Peru, promethazine HCl, perfume mix, fentichlor, chlorhexidine digluconate, and chlorpromazine HCl were the common photoallergens that elicited a positive response. Twenty-one of the 35 patients (70%) showed allergy to nickel, chrome, and/or ammoniated mercury. Noticeably, photoallergens such as balsam of Peru, perfume mix, cobalt, and captan revealed positive reactions in the patch tests, too. CONCLUSION: In 77.1% and 74.3% of CAD patients, photoallergens and allergens were identified, respectively. Among them, 57.1% showed positive reactions including both photopatch and patch tests. After the most frequent photoallergens, perfume and spices, and phenothiazines or related antihistamines ranked next and were found to be a unique characteristic to Korea. Photopatch and patchtests are the method for detecting photoallergens and allergens as important initiating agents and are the diagnostic tool for the epidemiologic study of CAD.

Degradaçäo de clorotalonil e captan em morangos in natura estocados em geladeira a 5§C / Degradation of chlorothalonil and captan in strawberries after storage at low temperature a 5§C

Resíduos de captan e clorotalonil foram quantificados em morangos "in natura" após três e sete dias de estocagem em geladeira -5oC . As amostras analisadas foram coletadas na CEASA de Campinas e também obtidas após cultivo em estaçäo experimental

An Epidemiological Study of Contact Dermatitis in Korea ( 1986 - 1993 ) / 대한피부과학회지

BACKGROUND: The first multicenter study on standard patenest results(1983-1986) was tried in Korea. Since then 10 years have elapsed and epidemiologi al data need be updated continuously. OBJECTIVE: To register and compile the results of patch the ig throughout the country and to compare the positivity ard trend with those of previous study. METHODS: Standard patch testings were performed using irachamper on Scanpor tape. The results were analysed by a personal computer program. RESULTS: A total of 2326 patch tested cases(male 539, female 1787) were compiled and analysed. The highest ag distribution was 3rd decade. As the job distribution, housewives and office workers were the mast frequent consisting 33.4% and 12.1% respectively. The face was the most frequently affected site comprising 49.6%. The highesteritization rates were foud with nickel(17.9%), cobalt(13.8%), fragrance mix(12.9%), potass ur dichromate(11.3%), ammoniated mercury(8.7%), neoaycin(7.2%). The lowest positivity inclured black rubber mix(1.0%), primin (1.2%), ethylenediarnine(1.3%), carba mix(1.4%), While nicel epoxy resin and 4-t-butylphenol formaldehyde resin showed increased reactivities, PPD, bacrubber mix, balsam of Peru, quaternium 15, ammceniatct mercury and captan showd a deceased tendency when compared with those of previous study. CONCLUSION: The large scale studies of epidemiology in cortat dermatitis have been performed and they need to be updated and analysed consecutively in the future.

Avaliaçäo da ecotoxicidade do fungicida Captan, através do estudo comparativo entre duas espécies de Oligochaetas edáficos (Amynthas kawayanus, Rosa-1891 e Eisenia foetida, Savigny-1826) / Evaluation of the ecotoxicity of the Captan fungicide, through the comparative study between 2 species of Oligochaetas edáficos (Amynthas kawayanus, Rosa-1891 e Eisenia foetida, Savigny-1826)

Duas espécies de Oligochaetas edáficos foram avaliadas para determinar a CL50 através do método "ARTISOL" adaptado, utilizando-se quatro formulaçöes distintas do fungicida CAPTAN. Os resultados obtidos indicaram variabilidade entre as espécies, demonstrando que agentes químicos podem afetar diferentemente organismos do mesmo grupo. Portanto, a utilizaçäo de grupos representativos da pedofauna em biotestes confirma a necessidade de aprimorar novas técnicas, com o objetivo de fornecer resultados efetivos que possibilitem entender melhor o grau de toxicidade dos químicos.

Estudo da influência de agrotóxicos sobre o desenvolvimento do Rhizobium leguminosarum biovar phaseoli / Study of the agrotoxics influence over the development of the Rhizobium leguminosarum biovar phaseoli

As bactérias fixadoras de nitrogênio atmosférico, via processo simbiótico, repassam N2 às leguminosas sob forma de amônia, proporcionando aumento na produçäo de alimentos protéicos, reciclagem biológica de nitrogênio do ar, evitando o alto custo da adubaçäo nitrogenada e o efeito potencialmente poluidor do nitrato lixiviado. Testou-se quatro estirpes de Rhizobium phaseoli frente a quatro fungicidas indicados para o tratamento de sementes de Phaseolus vulgaris L. (feijoeiro), no Estado do Rio Grande o sul (Brasil). Considerando-se as dosagens recomendadas dos fungicidas, houve crescimento bacteriano das quatro estirpes frente a Benomil e inibiçäo total frente a Captan; porém, para PCNB e Thiram, a resistência dependeu do tipo de estirpe. Observou-se que näo há influência de fungicidas sobre o desenvolvimento do Rhizobium phaseoli quando seleciona-se a estirpe adequada ao fungicida corretamente dosado.