RESUMO
Metastasis is an infrequent cause of tumor involvement of the major duodenal papilla and of cholestasis. We report a case of obstructive jaundice due to a metastatic breast carcinoma to the major duodenal papilla, and assess curative and palliative treatment that interventional endoscopy can offer.
La metástasis es una causa infrecuente de compromiso de la papila mayor y colestasis. Reportamos una causa rara de ictericia causada por metástasis de cáncer de mama en la papilla mayor duodenal.
Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Ampola Hepatopancreática , Neoplasias da Mama/patologia , Carcinoma Lobular/secundário , Neoplasias Duodenais/secundárioRESUMO
We report a rare presentation of an initially misdiagnosed case of a pseudotumor, which on histopathology was diagnosed as bilateral breast metastases of lobular carcinoma involving multiple extraocular muscles. A 61-year-old lady presented with external ophthalmoplegia and diplopia. Incisional biopsy was performed using a lid crease approach and the patient received radiotherapy and hormonal therapy. Following prolonged hormonal therapy, complete remission was achieved, with improvement in ocular motility and resolution of diplopia, about 18 months after the initial presentation. Multiple extraocular muscle involvement by breast carcinoma metastasis is very rare and should be considered in the differential diagnosis, especially in patients with a prior history of breast carcinoma.
Assuntos
Biópsia , Neoplasias da Mama/patologia , Neoplasias da Mama/terapia , Carcinoma Lobular/diagnóstico , Carcinoma Lobular/secundário , Carcinoma Lobular/terapia , Terapia Combinada , Diagnóstico Diferencial , Neoplasias Oculares/diagnóstico , Neoplasias Oculares/secundário , Neoplasias Oculares/terapia , Feminino , Seguimentos , Humanos , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Neoplasias Musculares/diagnóstico , Neoplasias Musculares/secundário , Neoplasias Musculares/terapia , Estadiamento de Neoplasias , Músculos Oculomotores , Fatores de TempoRESUMO
We report here a case of 40-year-old female admitted in view of bilateral ovarian tumors. There was past history of modified radical mastectomy. CT scan revealed a uterine cervicalfibroid in addition to bilateral adnexal masses. Lobular carcinoma metastasis were seen in the leiomyoma as well as in the bilateral ovaries. Metastasis of ductal carcinoma to uterine leiomyoma have been reported in literature. The present case is unique in two ways--(1) metastasis of lobular carcinoma (2) occurring in a cervical leiomyoma.
Assuntos
Adulto , Neoplasias da Mama , Carcinoma Lobular/secundário , Feminino , Humanos , Leiomioma/patologia , Neoplasias do Colo do Útero/patologiaRESUMO
We report a 56-year-old lady with chronic diarrhea and weight loss. She had undergone lumpectomy with axillary clearance (node positive) four years ago for invasive lobular carcinoma of breast. Investigations revealed involvement of almost the entire gut with skip areas. Biopsies from the stomach showed presence of signet-ring cells, suggestive of metastases from invasive lobular carcinoma of breast. Estrogen receptor immuno-staining was positive, confirming the diagnosis. She was treated initially with octreotide and later with chemotherapeutic agents, with transient relief in diarrhea. She succumbed eight months later.