Ductal eccrine carcinoma of the axilla: a diagnostic pitfall

Abstract: Ductal eccrine carcinoma (DEC) is a rare sweat gland carcinoma with ductular differentiation. Clinically, it is characterized by a slowly growing, hardened plaque or nodule predominantly located on the head and neck. Histologically, DEC shares similar features to invasive breast carcinoma, thus causing great diagnostic challenges. We report a 69-year-old woman who presented with a hardened plaque on the axilla. A skin biopsy was performed and metastatic invasive breast carcinoma could not be ruled out. Complete excision and further workup were subsequently conducted, leading to the diagnosis of estrogen receptor positive DEC with associated axillary lymph node metastases. The patient received adjuvant radiotherapy to the left axilla and was started on oral letrozole. She is disease-free 14 months after initial diagnosis.

Carcinoma anexial microquístico: tratamiento exitoso con extirpación quirúrgica amplia / Microcystic adnexal carcinoma: successfull treatment with wide surgical excision

El carcinoma anexial microquístico, también llamado carcinoma esclerosante de conductos sudoríparos, fue descripto por primera vez por Goldstein y cols. en 1982. Desde entonces varias presentaciones de este tumor han ayudado a definir sus características. Nosotros publicamos un caso de presentación clínica e histopatológica típica y hacemos una revisión de la literatura poniendo énfasis en el tratamiento que en nuestro caso se efectuó mediante la extirpación quirúrgica amplia de la lesión