1.
Saudi Medical Journal. 2006; 27 (9): 1302-1305
em Inglês
| IMEMR
| ID: emr-80919
RESUMO
Some heat shock proteins HSPs, act as molecular chaperones. These and other molecular chaperones that are not HSPs, function in a variety of protein biosynthetic event and protect proteins from the deleterious effects of stressors by stabilizing, and refolding proteins. They assist protein folding, assembly, transport and degradation. Several human diseases such as neurodegeneration, cancer, aging, retinal dystrophy, and inflammation arise from defects HSPs and protein folding. This review demonstrates the chaperones such as properties of HSPs in cellular processes and their implication in different kind of human diseases
Assuntos
Humanos , Chaperonas Moleculares/fisiologia , Doença/etiologia , Encéfalo/fisiopatologia , Neoplasias/metabolismo , Doenças Neurodegenerativas/metabolismo , Doenças Autoimunes/metabolismo , Doenças Cardiovasculares/metabolismo
2.
J Biosci
; 2005 Sep; 30(4): 461-4
Artigo
em Inglês
| IMSEAR
| ID: sea-111175