A study in extraction method of buprenorphine in urine / 法医学杂志

OBJECTIVE@#The extraction method for separating buprenorphine from urine was described.@*METHODS@#Buprenorphine was extracted with chloroform at pH7 or with SPE (extracted by organic support 401 at pH10.8, then eluted with chloroform), finally determined by GC-NPD.@*RESULTS@#The extracted yields of the analyte in specimens were 86.6% by solution-phase extraction and 83.0% by solid-phase extraction (SPE) respectively.@*CONCLUSION@#These two methods are simple and accurate for separating buprenorphine from urine.