The diagnosis and treatment of tibial intercondylar chondroblastoma

OBJECTIVES: To investigate the diagnosis and treatment of tibial intercondylar chondroblastoma. METHODS: We retrospectively analyzed the diagnosis and treatment of 12 patients with tibial intercondylar chondroblastoma admitted to the orthopedics department from May 2011 to February 2016; among them were 4 males and 3 females aged 10-19 years, with an average age of 15.7 years. Tibial intercondylar chondroblastoma was on the left and right side in 7 and 5 cases, respectively. The preoperative average Lysholm score of the knee joint was 68 (42-87). A posteromedial approach was applied in all cases. The incisions were approximately 5-8 cm in length. Complete curettage and inactivation were performed after fenestration, and allogeneic bone grafts were transplanted. Then, the posterior cruciate ligament insertion was fixed with 5.0 suture anchors. All patients were followed up with regularly to monitor for tumor recurrence, observe bone graft healing, and reassess the Lysholm score of the knee. RESULTS: Patients were followed for 7-55 months, and the median follow-up time was 19 months. One patient experienced tumor relapse 4 months after the operation. Incision, inactivation and cementation were performed. Then, the bone was fixed with anchors. In the other 11 patients, the bone graft healed over an average period of 6.2 months (4-10 months), with good functional recovery postoperatively. The average postoperative Lysholm score of the knee was 91 (81-95). CONCLUSION: Tibial intercondylar chondroblastoma has unique clinical and imaging characteristics and can effectively be treated by curettage followed by the inactivation, transplantation and fixation of allogeneic bone grafts with suture anchors through a posteromedial approach.

Condroblastoma de presentación atípica en concomitancia a osteomielitis crónica operado con cirugía radical: caso clínico / Chondroblastoma of atypical presentation in conjunction with chronic osteomyelitis operated through radical surgery: clinical case

INTRODUCCIÓN: El condroblastoma es un tumor óseo benigno representando menos del 1 por ciento del total de tumores óseos; se presenta principalmente en jóvenes. De etiología controversial, se desarrolla habitualmente en centros secundarios de osificación en huesos largos. No hay casos que describan su existencia junto a osteomielitis ni su tratamiento quirúrgico. CASO CLÍNICO: Mujer de 15 años con antecedente de osteomielitis de inicio reciente, diagnosticada con cintigrafía y biopsia en escápula izquierda; a pesar de tratamiento médico antibiótico con cloxacilina persiste dolor, eritema, impotencia funcional y aumento de volumen progresivo. Cintigrafía de control confirma nula respuesta a tratamiento inicial. Tomografía computada (TC) informa probable proceso tumoral osteolítico cortical con reacción de partes blandas en casi la totalidad de la escápula incluyendo cavidad glenoidea. Biopsia quirúrgica informa condroblastoma sospecha de variante agresiva resolviéndose con escapulectomía total con resección de cabeza humeral y posterior pexia clavículo-humeral. Biopsia definitiva de pieza quirúrgica informa osteomielitis crónica y condroblastoma agresivo. Evolución favorable en controles posteriores sin signos de recidiva local ni a distancia. DISCUSIÓN: La nula respuesta clínica al tratamiento inicial y su progresión hizo sospechar un proceso tumoral no diagnosticado inicialmente debido a que la biopsia no incluyó focos del condroblastoma. El manejo clásico del condroblastoma consiste en curetaje y relleno con autoinjerto; pero debido a la localización atípica, posibilidad de malignización y coexistencia con proceso osteomielítico crónico se optó por cirugía innovadora que consistió en resección total y posterior pexiaclavículo-humeral

INTRODUCTION: A Chondroblastoma is a benign bone tumor, corresponding to less than 1 percent of all bone tumors, and affecting mainly young people. Commonly developing in secondary centers of ossification in large bones, there are no cases describing its existence along with osteomyelitis, nor its surgical treatment. CLINICAL CASE: Woman (15 Y/O) with a history of osteomyelitis onset caused by a recent fall is diagnosed through scintigraphy and biopsy in the left scapule. Despite treatment with cloxacillin, pain persisted, erythema developed, with a progressive increase of volume and functional impotence. Control scintigraphy confirms no response to initial treatment. Computed Tomography (CT) informs of a probable cortical osteolysis tumoral process with soft tissue reactions in almost the entire scapule including glenoid cavity. Surgical biopsy shows chondroblastoma and, suspecting an agressive variant, it is resolved to perform a total scapulectomy with resection of scapule head and subsequent humerus-claviclepexia. Definitive biopsy of surgical piece shows chronic osteomyelitis and agressive chondroblastoma. The evolution of the patient is normal on follow-up controls, not presenting any signs of local neither distant relapse. DISCUSSION: The non-existence of a response to the initial treatment and its progression made us suspect of a natural process that was not diagnosed initially because the biopsy didn't include chondroblastoma focus. The usual chondroblastoma treatment consists of curetting and autograft filling; but due to the atypical location, and the possibility of coexistence with malignant and chronic osteomyelitic process we chose to apply an innovative surgery that consisted of total resection and subsequent pexia.

Condroblastoma de la cabeza femoral y reconstrucción con aloinjerto osteocondral: Reporte de caso / Femoral head chondroblastoma and reconstruction with osteochondral allograft: Case report

El condroblastoma de la cabeza femoral es un tumor poco frecuente (aproximadamente 1 o 2% de los tumores benignos de hueso), se presenta con mayor frecuencia en pacientes jóvenes de sexo masculino. El condroblastoma es más frecuente en el húmero proximal, fémur proximal, fémur distal y tibia proximal. La cabeza femoral es el tercer sitio más frecuente, No existe un tratamiento específico para esta entidad; se han descrito desde osteotomías acetabulares, injertos osteocondrales, injertos vascularizados de peroné, etcétera, todos reportando buenos resultados. Pero es clínicamente impredecible si no recibe tratamiento. Se presenta un caso que se manejó con aloinjerto osteocondral y la evolución de tres años posterior al procedimiento quirúrgico...

Femoral head chondroblastoma is an infrequent tumor, accounting for approximately 1-2% of benign bone tumors. It occurs more frequently in young male patients. It's most frequent locations include the proximal humerus, proximal femur, distal femur and proximal tibia. The femoral head is the third most frequent site of this tumor. There is no specific treatment for this entity; reported treatments range from acetabular osteotomies and osteochondral grafts, to vascularized fibular grafts, all of them with good results. However, this tumor is clinically unpredictable if left untreated. We report a case managed with osteochondral graft and followed-up for three years after the surgical procedure...

Ventana oncologica 11 / Window 11 oncological

En este caso se practicó una biopsia por aguja que confirmo el diagnóstico: Condroblastoma del Talo Izquierdo. En este caso, se practicó, una osteotomía del maléolo interno, con prefresado de tornillos esponjosos se expuso la lesión respetando el cartílago, se usó luego fresado de alta velocidad, y fenolización al 30%, luego se reconstruyó el talo con un auto injerto de cresta iliaca; la paciente tiene 7 años de tratada, sin recurrencia local, y sin necrosis avascular del talo.

Frequency, presentation and postintervention prognosis of chondroblastoma

To evaluate the frequency of clinico-radiological presentation and the prognosis after treatment of chondroblastoma. Design: A descriptive, observational study. Place and Duration of Study :The study was carried out at the Department of Orthopaedic Surgery, JPMC, Karachi over the period of 16 years, January 1986 to June 2002. Methodology: Patients in teenage, presenting with signs and symptoms of a primary bone tumours, were included by retrospectively reviewing the tumour registry record. Detailed scrutiny of clinical record was carried out to analyze the clinico radiological presentation and posttreatment prognosis criteria of healing was symptom-free centripetal and homogenous ossification. Seven [1.24%] out of 563 primary bone tumour cases were chondroblastoma. The clinico-radiological presentation in the 2 out of 7 [28.57%] cases was classical, 2 simulated osteomyelitis and other 3 as chondromyxoid fibroma, aneurysmal bone cyst and giant cell tumour. Lesions were treated with curettage and bone grafting. One patient [14.28%] developed recurrence within 2 years after curettage and healed after re-curettage and bone grafting. Five out of 7 [71,42%] tumours showed good response and 2 out of 7[28.57%] showed satisfactory response. Chondroblastoma is very rare benign primary bone tumour with high local recurrence rate. The lesions confined to epiphysis of weight-bearing bone present early with symptoms of mild arthritis. Lesions in non-weight -bearing bones often present late and simulates epiphysio-metaphyseal tumours. Lesions heals with centripetal healing and need more than 2 years follow-up to achieve recurrence-free healing

Comportamiento del condroblastoma de astrágalo en un basquetbolista: reporte de un caso y revisión de la literatura / Behavior of talus chondroblastoma in a basketball player: case report

La presencia de este tipo de tumores en el pie es extremadamente raro y sólo algunos han sido reportados. La forma de presentarse en este deportista y su evolución totalmente benigna a pesar de su aspecto, estimula al cirujano ortopedista a una resección quirúrgica amplia en estos casos

Condroblastoma: estudo clínico, radiográfico e tratamento cirúrgico / Chondroblastoma: clinical and radiographic study and surgical treatment

Os autores estudam 45 casos de condroblastoma tratados no Instituto de Ortopedia e Traumatologia da FMUSP entre 1950 e 1995. Há predileçao para a segunda década de vida e prevalência maior no sexo masculino em relaçao ao feminino (1,36:1). A dor é o principal sintoma encontrado. Do ponto de vista radiográfico, a lesao apresenta-se radioluzente, excêntrica, com margem esclerótica fina e, em 56,2 por cento dos casos, com reaçao periosteal. Os autores concluem ser o condroblastoma uma neoplasia de comportamento agressivo local e que a ressecçao marginal apresenta bom resultado oncológico e funcional.

Condroblastoma benigno do osso occipital: relato de caso / Benign chondroblastoma of the occipital bone: a case report

Condroblastoma benigno é tumor ósseo raro, tendo como origem células cartilagíneas. Classicamente este tumor acomete regioes epifisárias de ossos longos, sendo incomum o envolvimento de ossos do crânio, principalmente o osso occipital. Relatamos o caso de uma paciente com 16 anos de idade, com diagnóstico de condroblastoma benigno do osso occipital e discutimos os principais aspectos deste tumor.

Fibroma condromixóide da coluna torácica: relato de caso e revisäo da literatura / Chondromyxoid fibroma of the spinal cord: a case report and review of the literature

Os autores relatam o caso de compressao medular torácica da quinta articulaçao costovertebral à direita. O diagnóstico pré-operatório, com mielotomografia, foi de processo expansivo intrarraquidiano extradural ao nível de T5. Feita a abordagem cirúrgica por laminectomia, com ressecçao apenas da lesao intrarraquidiana. O diagnóstico de fibroma condromixóide somente foi definido com o estudo histopatológico. A paciente teve importante melhora neurológica. Decidiu-se pelo acompanhamento clínico e radiológico. Após dois anos houve recidiva do processo para dentro do canal raquidiano. Desta vez, foi realizada abordagem posterolateral à direita, por costotransversectomia e retirada da lesao. O diagnóstico histopatológico foi o mesmo. A paciente evoluiu com melhora neurológica e está sendo feito o seguimento há dois anos. Chamamos a atençao para a raridade do caso e discutimos a conduta.

Condroblastoma distal del fémur tratados con endoprótesis no convencionales: informe de dos casos con complicaciones / Distal chondroblastoma of the femur treated by non-conventional endoprosthesis: report two cases with complications

Se presentan dos casos de condroblastoma distal del fémur en pacientes del sexo femenino, de 11 a 12 años de edad, tratadas ambas con prótesis tumoral no convencional, la primera fue constreñida tipo Fabroni y la segunda fue la diseñada por Cortés en el Hospital Infantil de México, telescopiable. La respuesta inmediata al tratamiento fue satisfactoria en ambos casos pero los dos sufrieron complicaciones locales, en el primero por infección y exposición de la prótesis y en el segundo por colocación inapropiada de los componentes del segmento protésico femoral. Ambos se sometieron a cirugía complementaria