Condrocalcinosis axial: reporte de un caso / Axial chondrocalcinosis: a case report

La artropatía por pirofosfato de calcio (CPPD) se caracteriza por la acumulación de cristales de pirofosfato de calcio en el tejido articular y periarticular. La localización más frecuente son rodillas, muñecas y pelvis. Sin embargo, también existen reportes aislados de compromiso de columna. Se presenta el caso de un paciente varón de 52 años, con antecedentes de doble prótesis de caderas por coxartrosis diagnosticada a los 20 años de edad. Es evaluado en reumatología en febrero de 2017, por cuadro de poliartralgias de grandes articula-ciones, asociada a dolor de columna cervical, dorsal y lumbar. Se realizan exámenes imagenológicos que demuestran la presencia de calcificaciones interdiscales con sobrecrecimiento óseo, secundario a artrosis severa y discreta este-nosis raquídea solo en segmentos lumbares bajos.

The Calcium pyrophosphate dihydrate (CPPD) deposition disease is characterised by the deposition of crystals of CPPD in the articular as well as in periarticular structures. The most frequent location are knees, wrist and pelvis. However, also there are iso-lated cases involving the spine. It presents the case of a 52 years male patient, with history of bone arthrosis dou-ble hips prosthesis by bone arthrosis diagnosed 30 years ago. He is evaluated in feb-ruary 2017 by pain of large joints associated cervical spine pain dorsal and lumbar. Imagenological tests are prerfomed and confirms the presence of intervertebral discs calcifications and bone overgrowth secundary to severe osteoarthrosis and spinal ste-nosis in lower lumbar segments.

A Case of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease Presenting as an Acute Polyarthritis

We report a case of calcium pyrophosphate dihydrate crystal deposition disease (CPDD) presenting as an acute polyarthritis. A 66-yr-old woman was admitted with a 5-day history of fever and multiple joint pain including wrists, elbows, shoul-ders, knees, and ankles developed 5 days before admission. Her plain radiographs of wrists, elbows, shoulders, knees, and ankles showed chondrocalcinosis. The pubic symphysis, lumbar intervertebral discs, and both hip joints, which were asymptomatic, also had calcium deposits. The compensated polarized microscopic examination of the joint fluid, aspirated from the right knee revealed intracellular and extracellular weakly positive birefringent crystals, confirming the CPDD. This case showed that CPDD may manifest as an acute polyarthritis mimicking acute onset rheumatoid arthritis.

study of chondrocalcinosis in osteoarthritis of the knee

One hundred patients with clinical and radiographic evidence of osteoarthritis [OA] of the knee were studied for the presence of articular chondrocalcinosis [ACC]. 5 patients had ACC, 3 females and 2 males their age ranged from 55 to 75 years. 4 of then had unilateral ACC involving the lateral compartment of the right knee joint and only one had bilateral ACC. The prevalence of ACC increases with age. A possible relationship was found between the severity of radiographic changes of OA and the development of chondrocalcinosis