Articulación temporomandibular ¿disco o menisco articular? / Temporomandibular joint, disc or articular meniscus

Los términos disco y menisco se encuentran en Terminologia Anatomica. Sin embargo, ambos términos son utilizados como sinónimos para referirse al cartílago intraarticular presente en la articulación temporomandibular (ATM). Por este motivo, el objetivo de este estudio es exponer las raíces griegas de los términos disco y menisco para evaluar la coherencia entre su relación léxica y su relación morfológica. Ambos términos fueron consultados en el Programa Federativo Internacional de Terminología Anatómica y en diccionarios de idiomas griego, español e inglés. La búsqueda reportó que el término "disco" deriva del latín discus, y este a su vez del griego δίσκος [dískos] que significa "cuerpo cilíndrico cuya base es muy grande respecto a su altura". Por su parte "menisco" proviene del griego mēnískos μηνίσκος [mḗn μήν gr. μείς 'meis', 'luna creciente' + -iskos gr. Sufijo diminutivo 'pequeño'] que significa "luna creciente pequeña" y se define como "cartílago de forma semilunar y de espesor menguante de la periferia al centro; forma parte de la articulación de la rodilla". Por lo tanto, la definición anatómica de disco articular y menisco está determinada por su morfología según la etimología de la palabra. En la ATM se encuentra un disco articular entre los huesos articulares, según su morfología.

SUMMARY: The terms disc and meniscus are found in Terminologia Anatomica. However, both terms are used synonymously to refer to the intra-articular cartilage present in the temporomandibular joint (TMJ). For this reason, this study aims to expose the greek roots of the terms disc and meniscus to evaluate the coherence between their lexical and morphological relationships. Both terms were consulted in the International Federative Program of Anatomical Terminology and in Greek, Spanish and, English dictionaries. The search reported that the term "disc" derives from the Latin discus, and this in turn from the Greek δίσκος [dískos], which means "cylindrical body whose base is very large compared to its height". For its part, "meniscus" comes from the Greek mēnískos μηνίσκος [mḗn μήν gr. μείς 'meis', 'crescent moon' + -iskos Gr. Diminutive suffix 'small'] which means "small crescent moon" and, is defined as "cartilage with a semilunar shape and decreasing thickness from the periphery to the center; It is part of the knee joint. Therefore, the anatomical definition of articular disc and meniscus is determined by its morphology according to the etymology of the word. In the TMJ, an articular disc is found between the articular bones, depending on their morphology.

Magnetic resonance imaging texture analysis of the temporomandibular joint for changes in the articular disc in individuals with migraine headache / Análise de textura por ressonância magnética da articulação temporomanbibular com alterações no disco articular em individuos com cefaleia migranea

Objective: the aim of this study was to analyse the performance of the technique of texture analysis (TA) with magnetic resonance imaging (MRI) scans of temporomandibular joints (TMJs) as a tool for identification of possible changes in individuals with migraine headache (MH) by relating the findings to the presence of internal derangements. Material and Methods: thirty MRI scans of the TMJ were selected for study, of which 15 were from individuals without MH or any other type of headache (control group) and 15 from those diagnosed with migraine. T2-weighted MRI scans of the articular joints taken in closed-mouth position were used for TA. The co-occurrence matrix was used to calculate the texture parameters. Fisher's exact test was used to compare the groups for gender, disc function and disc position, whereas Mann-Whitney's test was used for other parameters. The relationship of TA with disc position and function was assessed by using logistic regression adjusted for side and group. Results: the results indicated that the MRI texture analysis of articular discs in individuals with migraine headache has the potential to determine the behaviour of disc derangements, in which high values of contrast, low values of entropy and their correlation can correspond to displacements and tendency for non-reduction of the disc in these individuals. Conclusion: the TA of articular discs in individuals with MH has the potential to determine the behaviour of disc derangements based on high values of contrast and low values of entropy (AU)

Objetivo: o objetivo deste estudo foi analisar o desempenho da técnica de análise de textura (AT) em exames de ressonância magnética (RM) das articulações temporomandibulares (ATM) como ferramenta para identificação de possíveis alterações em indivíduos com cefaléia migrânea (CM) relacionando os achados com a presença de desarranjos internos. Material e Métodos: trinta exames de RM das ATM foram selecionados para estudo, sendo 15 de indivíduos sem cefaleia migrânea ou qualquer outro tipo de cefaléia (grupo controle) e 15 diagnosticados com CM. As imagens de RM ponderadas em T2 das articulações realizadas na posição de boca fechada foram usadas para AT. A matriz de co-ocorrência foi usada para calcular os parâmetros de textura. O teste exato de Fisher foi usado para comparar os grupos quanto ao sexo, função do disco e posição do disco, enquanto o teste de Mann-Whitney foi usado para os demais parâmetros. A relação da AT com a posição e função do disco foi avaliada por meio de regressão logística ajustada para lado e grupo. Resultados: a AT por RM dos discos articulares em indivíduos com cefaleia migrânea tem o potencial de determinar o comportamento dos desarranjos discais, em que altos valores de contraste, baixos valores de entropia e sua correlação podem corresponder a deslocamentos e tendência a não redução do disco nesses indivíduos. Conclusão: a análise de textura dos discos articulares em indivíduos com CM tem potencial para determinar o comportamento dos desarranjos do disco com base em altos valores de contraste e baixos valores de entropia. (AU)

Evaluation of the relationship between the attachment type of lateral pterygoid muscle and the position of temporomandibular joint disc in patients with temporomandibular joint disorders based on wireless amplified MRI detector high resolution imaging / 中华口腔医学杂志

Objective: To explore the correlation between the attachment type of lateral pterygoid muscle (LPM) and the position of temporomandibular joint (TMJ) disc in patients with temporomandibular disorders (TMD) by using wireless amplified magnetic resonance imaging detector (WAND) coupled with conventional head and neck joint coil for high resolution imaging of TMJ. Methods: Eighty-five patients with TMD diagnosed by oral and maxillofacial surgeons of Guizhou Provincial People's Hospital from October 2019 to January 2022 were collected. A total of 160 TMJ were included. There were 16 males and 69 females, aged (32.7±14.2) years. All patients were scanned with open, closed oblique sagittal and coronal WAND coupled head and neck coils with bilateral TMJ. Based on TMJ and LPM high resolution imaging, to explore the correlation between LPM attachment types and the position of TMJ disc in TMD patients, and to evaluate the potential clinical value of LPM attachment types in TMD patients. χ2 test and Pearson correlation analysis were used to evaluate the correlation between LPM attachment type and TMJ disc location. Results: There were three types of LPM attachment: type Ⅰ in 51 cases [31.9% (51/160)], type Ⅱ in 77 cases [48.1% (77/160)] and type Ⅲ in 32 cases [20.0% (32/160)]. There was a significant correlation between the type of LPM attachment and the position of articular disc (χ2=28.20, P=0.002, r=0.776). There was no statistical significance between the type of LPM attachment and the reversible displacement of articular disc (χ2=0.24, P=0.887, r=0.825). Conclusions: There is a correlation between the attachment type of LPM and the position of the disc in TMD patients. WNAD coupled with conventional head and neck joint coil TMJ high resolution scan can provide reliable imaging evidence for TMD patients in evaluating the type of LPM attachment and the location of disc.

Discopexia e fisioterapia no tratamento do deslocamento de disco articular sem redução / Discopexy and physiotherapy in the treatment of articular disc displacement withou reduction

A articulação temporomandibular está vunerável a várias condições de anormalidades já bastante conhecidas, dentre elas, o deslocamento do disco articular sem redução, considerado pela literatura o mais comum das patologias desta região. A deterioração do quadro pode ser um indicativo da necessidade cirúrgica. Em específico, no deslocamento de disco sem redução, o reposicionamento definitivo pode ser adquirido através de discopexia e artrocentese. O presente trabalho tem como objetivo relatar um caso clínico de deslocamento de disco articular bilateral sem redução, apresentando a importância da fisioterapia associada à abordagem cirúrgia na recuperação da função mandibular, bem como, reforçar a importância de uma abordagem conjunta entre análise clínica e imaginológica para resolução de casos. Paciente feminino cursando com diversos sintomas em face e pescoço de forma progressiva ao longo de dois anos foi submetida a cirurgia na articulação temporo-mandibular, onde foi feita a discopexia através de ancoragem dos discos articulares com parafusos. A avaliação física, assim como, a imaginológica, ajudaram na confirmação do diagnóstico. A abordagem cirurgica adotada no tratamento deste caso foi descrita na literatura desde o final do século XIX. Conclui-se que, o método utilizado no tratamento do deslocamento de disco sem redução deve ser baseado nos sinais e sintomas do paciente, cuja abordagem deve ser readequada de acordo com as mudanças do quadro apresentado. Nesta análise, a abordagem cirúrgica associada à fisioterapia específica para as estruturas musculoesquelética da face trouxeram resultados positivos(AU)

The temporomandibular joint is responsible for several well-known conditions of abnormalities, among them, the joint disc displacement without reduction, considered by the literature the most common pathology of this region. Deterioration of the condition may be indicative of surgical need. Specifically, in displacement disc without reduction, definitive repositioning can be achieved through discopexy and arthrocentesis. The aim of the present study is to report a case of unilateral articular disc displacement without reduction, as well the importance of physiotherapy associated with the surgical approach in the recovery of mandibular function, as well as reinforcing the importance of a joint approach between clinical and imaging analysis for case resolution. Female patient with several symptoms in the face and neck progressively over two years, underwent surgery in the temporomandibular joint, where discopexy was performed by anchoring the articular discs with screws. The physical assessment, as well as the imaging, helped to confirm the diagnosis. The surgical approach adopted in the treatment of this case has been described in the literature since the end of the 19th century. In conclusion, the method used to treat articular disc displacement without reduction should be based on the patient's signs and symptoms, whose approach should be readjusted according to the changes in the presented picture. In this analysis, the surgical approach associated with specific physiotherapy for the musculoskeletal structures of the face brought positive results(AU)

Mini suture anchor: An effective device for reduction and fixation of displaced temporomandibular joint disc with intracapsular condylar fracture / 中华创伤杂志(英文版)

PURPOSE@#The main aim is to provide clinical reference for the application of mini suture anchor in the reduction and fixation of displaced temporomandibular joint (TMJ) disc with intracapsular condylar fracture.@*METHODS@#From October 2018 to October 2019, 21 patients (31 sides) with intracapsular condylar fractures and articular disc displacement from West China Hospital of Stomatology, Sichuan University were included. The selection criteria were: (1) mandibular condylar fractures accompanied by displacement of the TMJ disc, confirmed by clinical examination, CT scan and other auxiliary examinations; (2) indication for surgical treatment; (3) no surgical contraindications; (4) no previous history of surgery in the operative area; (5) no facial nerve injury before the surgery; (6) informed consent to participate in the research program and (7) complete data. Patients without surgical treatment were excluded. The employed patients were followed up at 1, 3, 6 and 12 months after operation. Outcomes were assessed by success rate of operation, TMJ function and radiological examination results at 3 months after operation. Data were expressed as number and percent and analyzed using SPSS 19.0.@*RESULTS@#All the surgical procedures were completed successfully and all the articular discs were firmly attached to the condyles. The articular disc sufficiently covered the condylar head after the fixation. The fixation remained stable when the mandible was moved in each direction by the surgeons. No complications occurred. The functions of the TMJ were well-recovered postoperatively in most cases. CT scan revealed that the screws were completely embedded in the bone without loosening or displacement.@*CONCLUSION@#Mini suture anchor can provide satisfactory stabilization for the reduced articular disc and also promote the recovery of TMJ functions.

Multimodal imaging analysis of the cyst like lesion of condyle in temporomandibular joint / 中华口腔医学杂志

Objective: To investigate the imaging features of condylar cystic degeneration of temporomandibular joint (TMJ) by cone-beam CT (CBCT), spiral CT, MRI and radionuclide bone imaging. Methods: From January 2018 to December 2020, thirty-two patients with cyst-like lesions of condylein temporomandibular joint were examined by CBCT, spiral CT, MRI and radionuclide bone imaging at the Department of Oral and Maxillofacial Surgery in General Hospital of Chinese PLA. There were 12 males and 20 females involved, aged from 16 to 65 years with an average age of (33.9±12.5) years. The characteristics of CBCT, spiral CT, MRI and radionuclide bone imaging were analyzed. Condylar cyst like lesions were classified as type A and type B based on the presence or absence of surface bone defects. Condylar cyst like lesions were classified as type Ⅰ(yes) and type Ⅱ(no) according to the accompanying bone marrow edema-like lesions of the condyles. The incidence of condylar bone marrow edema, disc displacement and abnormal bone metabolism were analyzed. Results: A total of 64 joint images of 32 patients were included, including 34 sides with TMJ cyst-like lesion and 6 sides with multiple cyst-like lesions,the total cyst-like lesions were 42. The largest diameter of cyst-like lesion ranged from 1.0 to 12.4 mm, with an average length of (3.7± 1.8) mm. There were 24 cases of type A TMJ cyst like lesion and 10 cases of type B cyst-like lesion. The detection rate of CBCT was 95.2% (40/42) and that of spiral CT was 100% (42/42), there was no significant difference (Calibration Chi-square=0.51, P=0.474). The detection rate of nuclear magnetic resonance was 80.1% (34/42), and the detection rate of cyst-like lesions less than 2 mm was 3/11. In the cyst like lesion side, there were 9 sides with anterior disc displacement with reduction, 20 sides with anterior disc displacement without reduction. In the non-cyst like lesion side, 10 sides with anterior disc displacement with reduction and 6 sides with anterior disc displacement without reduction. There was a significant difference in the displacement of the disc between cyst-like and non-cystic lesion side (χ²=7.80, P=0.005). MRI showed that 6 cases of cystic side[17.6% (6/34)] had bone marrow edema-like lesions (all type A), 1 case of non-cyst like lesions side [3.3% (1/30)] had bone marrow edema-like lesion, there was no significant difference between cystic and non-cystic lesions (Calibration Chi-square=2.04, P=0.153). There was a significant difference between type A and B cystic lesions (Fisher exact probability method, P=0.024). Radionuclide bone imaging showed abnormal bone metabolism in 26 patients in the cyst-like lesion side and 5 patients in the non-cyst like lesion side (χ²=22.82, P<0.001). Conclusions Multi-slice Spiral CT could detect the cyst-like lesion of TMJ condyle in the early stage, which is different from the large joint. And the formation mechanism may vary from the different classifications.

Luxations temporo-mandibulaires au CHU de Bouaké: Aspects épidémiologiques, cliniques et thérapeutiques / Temporomandibular Dislocations in Bouake Teaching Hospital: Epidemiological, Clinical and Therapeutic Aspects

Introduction. Les luxations temporo-mandiblaires sont peu fréquentes au CHU de Bouaké, mais elles sont invalidantes. Les objectifs étaient de : Distinguer les aspects épidémiologiques, et d'identifi er les formes cliniques et les aspects thérapeutiques. Méthodes. Il s'agissait d'une étude rétrospective et descriptive qui s'est déroulée du 1er janvier 2018 au 30 décembre 2019 dans le service d'odontostomatologie et de chirurgie maxillo-faciale du Centre Hospitalier et Universitaire de Bouaké. Résultats. Quarante et un (41) cas ont été colligés soit une fréquence hospitalière de 5%. L'âge moyen était de 40,18 ans avec des extrêmes de 11 ans et 77 ans. Le sex-ratio était de 0,78. Le délai moyen de consultation était de 3 jours. Le bâillement représentait 48,78% des causes et avait pour facteur favorisant l'édentation partielle postérieures dans 90% des cas. Les luxations isolées de l'articulation temporo mandibulaire étaient observées dans 85,37% des cas, et étaient toutes antérieures. Parmi ces luxations isolées, 88,57% étaient bilatérales et 11,43% unilatérales. La luxation supérieure a été retrouvée dans 4,88% de cas, et elle était toujours associée à une fracture de la symphyse mandibulaire. Dans 80,49% des cas, le traitement a été orthopédique. L'évolution a été favorable dans 82,93% des cas. Conclusion. Les luxations temporo-mandibulaires sont des affections très invalidantes. Les absences dentaires constituent le principal facteur prédisposant d'où la nécessité d'une bonne réhabilitation dentaire prothétique afi n d'éviter les récidives.

Double-needle arthrocentesis with viscosupplementation in patients with temporomandibular joint disc displacement without reduction

OBJECTIVES: Arthrocentesis is the simplest surgical intervention for the temporomandibular joint (TMJ). It can be performed on an outpatient basis at a low cost and with low morbidity. The objective is to release the articular disc by disrupting the adhesion formed between its surfaces and the mandibular fossa through hydraulic pressure generated by irrigation of the upper compartment of the TMJ. Viscosupplementation with hyaluronic acid during or after arthrocentesis improves clinical outcomes, increases mouth opening, and reduces pain levels. The aim of this study was to evaluate the efficiency of arthrocentesis plus hyaluronic acid viscosupplementation through clinical examination and preoperative magnetic resonance imaging in patients with unilateral disc displacement without reduction (DDwoR). METHODS: This analytical retrospective cross-sectional study clinically and radiologically evaluated 72 patients of both sexes with unilateral DDwoR. The following data were collected: sex, pain, age, duration of pain, maximum mouth opening, and patient pain perception on a visual analog scale. TMJ arthrocentesis was performed only once for each of the indicated joints. Data were collected before arthrocentesis (baseline) and at 7, 14, 30, 60, 90, and 180 days after the procedure (final evaluation). RESULTS: Between the baseline and final evaluation, there was a significant reduction in pain (p=0.001) and restoration of articular function. In addition, there was a significant increase in maximum mouth opening (p=0.001). CONCLUSION: Patients with DDwoR undergoing arthrocentesis combined with hyaluronic acid injection showed significant improvement in the perceived pain and maximum mouth opening in the mid-term follow-up periods.

Effect of using Photobiomodulation, stabilization, and anterior repositioning splints on the pain level of subjects with temporomandibular joint disc displacement with reduction / Efeito do uso da terapia a laser de baixa potência, placas planas e placas reposicionadoras anterior, no nível de dor de indivíduos com deslocamento anterior do disco articular com redução

Objective: was to evaluate the effect of four conservative treatment modalities on the pain level of patients with temporomandibular joint (TMJ) anterior disc displacement with reduction (ADDwR). Material and methods:100 subjects (64 females and 36 males) were selected, divided into four groups, 25 patients of each. Subjects of Group I have been treated with behavioral therapy. Subjects of Group II had been treated with Photobiomodulation therapy (PBMT). Subjects of Group III had been treated by anterior repositioning splint (ARS). Subjects of Group IV had been treated by a stabilization splint. The pain was evaluated by visual analog score (VAS) from 0 to 10. Statistical analysis was done using one-way ANOVA test for comparison between groups. Within each group, a comparison between baseline and after treatment was done using paired t-test (p<0.05). Results: There was a statistical difference between the pain scores of the different groups after treatment (p≤0.05). Also, there were statistical differences between all groups (p≤0.05) except that between group II and group III (p˃0.05). Conclusion: The use of stabilization splint and ARS are effective non-invasive methods for reducing the pain level in the treatment of TMJ ADDwR cases.(AU)

Objetivo: avaliar o efeito de quatro modalidades de tratamento conservador no nível de dor de pacientes com deslocamento anterior do disco articular com redução. Material e Métodos: foram selecionados 100 indivíduos(64 mulheres e 36 homens), divididos em quatro grupos, 25 pacientes cada. Os indivíduos do Grupo I foram tratados com terapia comportamental. Os indivíduos do Grupo II foram tratados com terapia de fotobiomodulação. Os indivíduos do Grupo III foram tratados com placa de reposicionamento anterior. Os indivíduos do Grupo IV foram tratados com uma placa de estabilização. A dor foi avaliada pelo escala visual analógica (EVA) de 0 a 10. A análise estatística foi feita usando o teste ANOVA de uma via para comparação entre os grupos. Dentro de cada grupo, uma comparação entre a linha de base e após o tratamento foi feita usando o teste t pareado (p <0,05). Resultados: Houve diferença estatística entre os escores de dor dos diferentes grupos após o tratamento (p ≤ 0,05). Além disso, houve diferenças estatísticas entre todos os grupos (p ≤0,05), exceto entre o grupo II e o grupo III (p˃0,05). Conclusão: O uso de placa de estabilização e reposicionadora anterior são métodos não invasivos eficazes para reduzir o nível de dor no tratamento de casos de deslocamento anterior de disco articular sem redução.(AU)

Research progress on tissue engineering in repairing tempomandibular joint / 浙江大学学报·医学版

Temporomandibular joint osteoarthritis (TMJOA) is mainly manifested as perforation of temporomandibular joint disc (TMJD) and destruction of condylar osteochondral complex (COCC). In recent years, tissue engineering technology has become one of the effective strategies in repairing this damage. With the development of scaffold material technology, composite scaffolds have become an important means to optimize the performance of scaffolds with the combined advantages of natural materials and synthetic materials. The gelling method with the minimally invasive concept can greatly solve the problems of surgical trauma and material anastomosis, which is beneficial to the clinical transformation of temporomandibular joint tissue engineering. Extracellular matrix scaffolds technology can solve the problem of scaffold source and maximize the simulation of the extracellular environment, which provides an important means for the transformation of temporo joint tissue engineering to animal level. Due to the limitation of the source and amplification of costal chondrocytes, the use of mesenchymal stem cells from different sources has been widely used for temporomandibular joint tissue engineering. The fibrochondral stem cells isolated from surface layer of articular cartilage may provide one more suitable cell source. Transforming growth factor β superfamily, due to its osteochondrogenesis activity has been widely used in tissue engineering, and platelet-rich derivative as a convenient preparation of compound biological factor, gradually get used in temporomandibular joint tissue engineering. With the deepening of research on extracellular microenvironment and mechanical stimulation, mesenchymal stem cells, exosomes and stress stimulation are increasingly being used to regulate the extracellular microenvironment. In the future, the combination of complex bioactive factors and certain stress stimulation may become a trend in the temporomandibular joint tissue engineering research. In this article, the progress on tissue engineering in repairing COCC and TMJD, especially in scaffold materials, seed cells and bioactive factors, are reviewed, so as to provide information for future research design and clinical intervention.

Evaluation of Lateral Pterygoid Muscle Contraction in Patients with Temporomandibular Disorders Based on 3D-T2 Weighted Imaging / 中国医学科学院学报

Objective To evaluate lateral pterygoid muscle(LPM)contraction in the patients with temporomandibular disorders(TMD)based on 3D-T2 weighted imaging(3D-T2WI).Multiplanar reconstruction(MPR)was employed to measure the length of LPM in the images taken in closed-and open-mouth positions. Methods Seventeen TMD patients [age of(29.82±10.70)years,males/females=8/9] and 13 normal volunteers [control,age of(23.54±3.31)years,males/females=6/7] received 3D-T2WI of the temporomandibular joints in closed-and open-mouth positions from November 2019 to April 2020 in Department of Radiology,Hainan Hospital of Chinese PLA General Hospital.According to the position of the discs,the subjects were classified into the following groups:TMD with disc displacement without reduction(TMD-DDwoR),TMD with disc displacement with reduction(TMD-DDwR),TMD without disc displacement(TMDwoDD),and normal control without disc displacement(NCwoDD).MPR was employed to measure the maximal length of the superior belly of LPM.One-way analysis of variance,receiver operating characteristic curve,and permutation test were employed for the statistical analyses. Results The contraction of LPM was significantly shorter in TMD-DDwoR group [(3.36±1.96)mm] than in TMDwoDD group [(7.90±3.95)mm],NCwoDD group [(8.77±3.13)mm](

Caracterización clínica, imagenológica y quirúrgica de la discopexia en pacientes con artropatía discal de la art iculación temporomandibular. Estudio de serie de casos / Clinical, imagenological and surgical characterization of discopexia in patients with discal arthropathy of the temporomandibular articulation. Case series study

Introducción: El desplazamiento discal es la artropatía temporomandibular más común. Los desplazamientos discales sin Reducción (DDSR) constituyen una condición clínica en la cual en boca cerrada el disco articular se encuentra desplazado completamente, sin contacto con la vertiente anterior de la cabeza mandibular y en boca abierta el disco no es recapturado. El tratamiento quirúrgico realizado es la discopexia. A pesar de toda la información presente en la bibliografía aún existe controversia entre la elección de tratamiento del DDSR. Objetivo: Presentar la experiencia clínica, quirúrgica e imagenológica de la discopexia en DDSR mediante la presentación de una serie de casos. Metodología: Se realizó un estudio retrospectivo de las historias clínicas del Servicio de Cirugía Bucal y Maxilofacial del hospital General del Oeste "Dr. José Gregorio Hernández", Distrito Capital, Venezuela, entre 2014-2018; se seleccionaron seis casos clínicos que presentaban DDSR, los cuales fueron intervenidos con discopexia, posteriormente se evaluaron clínica e imagenológicamente. Resultados: Los seis casos presentaron particularidades en el transcurso del tratamiento desde la fase inicial y en la postoperatoria. Se evidenció una franca mejoría en las manifestaciones clínicas, en contraste, la resonancia magnética postoperatoria, el cual reveló el desplazamiento discal nuevamente. Conclusiones: La estabilidad en la reubicación discal postoperatoria depende de múltiples factores, tales como la estabilidad oclusal, muscular y presencia de hábitos parafuncionales. El aumento en la apertura bucal fue la característica común en todos los pacientes de este estudio así como la disminución de la sintomatología dolorosa.

Introduction: Disc displacement is the most common temporomandibular arthropathy. The displacements without reduction (DDSR) become a clinical practice in the closed mouth the articular disc is completely displaced, without contact with the anterior vertical of the mandibular head and in the open mouth the disc is not recaptured. The surgical treatment performed is discopexy. Despite all the information present in the literature there is still controversy between the choice of treatment of the DDSR. Objective: To present the clinical, surgical and imaging experience of discopexy in DDSR by presenting a series of cases. Methodology: A retrospective study of the clinical records of the Oral and Maxillofacial Surgery Service of the General del Oeste Hospital "Dr. José Gregorio Hernández ", Capital District, Venezuela, between 2014-2018; Six clinical cases were selected that presented DDSR, which were operated on with discopexy, and then evaluated clinically and imaging. Results: The six cases present particularities in the course of the treatment from the initial phase and in the postoperative period. The evidence is improved in the clinical manifestations, in contrast, in the postoperative magnetic resonance, in the articular disc it moved again. Conclusions: Stability in postoperative disc relocation depends on multiple factors, such as occlusal stability, muscle stability and the presence of parafunctional habits. The increase in oral opening was the common feature in all the patients for this study, as well as the decrease in painful symptoms.

Disc stability after condylar discopexy with open surgery technique: a case report

Of the temporomandibular joint (TMJ) pathologies, temporomandibular disorders (TMD) of discdisplacement present several clinical signs and symptoms, the main ones being joint pain me-asured with the visual analogue scale (VAS) reporting on average VAS>6, and functional inca-pacity measured in mm of mouth opening, reporting on average <30mm in cases of TMD. The present case corresponds to a patient with limitation of mouth opening <15mm, joint pain VAS= 8, and functional limitation. The subject's condition was diagnosed clinically and by magnetic resonance imaging (MRI). The patient presented a Wilkes VI lateral dislocation of the left cond-yle disc without reduction, treated with open surgery discopexy, with disc fixation by monocryl suture and retrodiscal thermocoagulation. The patient showed a significant improvement in the removal of pain and in joint function. In clinical checkups at 1 month, 3 months, 6 months and 1 year, the patient showed decrease of pain levels, from VAS= 8 to VAS= 0, and mouth opening of <15mm to 36mm in the last checkup. Clinical and imaging evaluation at 4 years shows disc stability, with maximum mouth opening of 36 mm, with no disc displacement and clinically asymptomatic VAS = 0. In this case, discopexy with open surgery achieved improvements in functional capacity and removal of pain at short term. Long-term stability was associated with anatomical functions without alteration and without relapse of the symptomatology.

Discopexia bilateral em paciente edêntula com dor orofacial / Bilateral discopexy in edentulous patient whit orofacial pain

A disfunção temporomandibular (DTM) pode acometer os músculos mastigatórios, articulação temporomadibular (ATM) e estruturas adjacentes. Os sintomas mais comuns são: dor na região da ATM e dos músculos da mastigação, mas, em casos mais graves, podem acometer outras regiões faciais, que afetam diretamente a qualidade de vida dos pacientes. Tanto as abordagens cirúrgicas como não cirúrgicas podem ser usadas dependendo da etiologia e gravidade da doença. O tratamento tem como objetivo aliviar os sintomas e, consequentemente, melhorar a qualidade de vida dos pacientes. Objetiva também descrever um caso no qual foi realizada a discopexia como alternativa cirúrgica em uma paciente que teve tratamentos conservadores mal sucedidos para aliviar a dor facial, discutindo as características dos distúrbios de articulação e as formas de tratamento. A paciente continuou com tratamento fisioterápico funcional e evoluiu sem queixas álgicas, relatando melhora na qualidade de vida. A abordagem cirúrgica não deve ser considerada a primeira escolha, quando houver dor facial, no entanto, sob condições de sintomas persistentes e crônicos, alternativas, como a discopexia e cirurgia na articulação temporomandibular, podem ser consideradas para benefício do paciente... (AU)

Temporomandibular dysfunction (TMD) can affect the masticatory muscles, temporomandibular joint (TMJ) and adjacent structures. The most common symptoms are pain in the TMJ region and chewing muscles, but in more severe cases can affect other facial regions that directly affect the quality of life of patients. Both surgical and non-surgical approaches may be used depending on the etiology and severity of the disease and the goal of treatment is to alleviate symptoms and thereby improve patients' quality of life. The aim of the present article is to describe a case where discopexy was performed as a surgical alternative in a patient who had unsuccessful conservative treatments to relieve facial pain, discussing the characteristics of joint disorders and treatment modalities. The patient continued with functional physiotherapeutic treatment and evolved without pain complaints, reporting improvement in quality of life. The surgical approach should not be considered the first choice when there is facial pain. However, under conditions of persistent and chronic symptoms, alternatives such as discopexy and temporomandibular joint surgery may be considered for the benefit of the patient... (AU)

Temporomandibular joint disc displacement with reduction: a review of mechanisms and clinical presentation

Abstract Disc displacement with reduction (DDWR) is one of the most common intra-articular disorders of the temporomandibular joint (TMJ). Factors related to the etiology, progression and treatment of such condition is still a subject of discussion. This literature review aimed to address etiology, development, related factors, diagnosis, natural course, and treatment of DDWR. A non-systematic search was conducted within PubMed, Scopus, SciELO, Medline, LILACS and Science Direct using the Medical Subjective Headings (MeSH) terms "temporomandibular disorders", "temporomandibular joint", "disc displacement" and "disc displacement with reduction". No time restriction was applied. Literature reviews, systematic reviews, meta-analysis and clinical trials were included. DDWR is usually asymptomatic and requires no treatment, since the TMJ structures adapt very well and painlessly to different disc positions. Yet, long-term studies have shown the favorable progression of this condition, with no pain and/or jaw locking occurring in most of the patients.

Chronic inflammation deteriorates structure and function of collagen fibril in rat temporomandibular joint disc / 国际口腔科学杂志·英文版

Collagen is the building component of temporomandibular joint (TMJ) discs and is often affected by inflammation in temporomandibular disorders. The macromechanical properties of collagen are deteriorated by chronic inflammation. However, the mechanism by which inflammation influences disc function remains unknown. The relationship between the ultrastructure and nanomechanical properties of collagen in inflamed discs should be clarified. Seven-week-old female Sprague-Dawley rats were randomly divided into two groups. Chronic TMJ inflammation was induced by intra-articular injection of complete Freund's adjuvant, and samples were harvested after 5 weeks. Picrosirius staining revealed multiple colours under polarized light, which represented alternative collagen bundles in inflamed discs. Using atomic force microscopy scanning, the magnitude of Young's modulus was reduced significantly accompanied with disordered collagen fibril arrangement with porous architecture of inflamed discs. Transmission electron microscopy scanning revealed a non-uniform distribution of collagen fibres, and oversized collagen fibrils were observed in inflamed discs. Fourier transform infrared microspectroscopy revealed a decrease in 1 338 cm/amide II area ratio of collagen in different regions. The peak positions of amide I and amide II bands were altered in inflamed discs, indicating collagen unfolding. Our results suggest that sustained inflammation deteriorates collagen structures, resulting in the deterioration of the ultrastructure and nanomechanical properties of rat TMJ discs.

Effects of staurosporine on the contraction of self-assembled constructs of goat temporomandibular joint disc cells / 华西口腔医学杂志

OBJECTIVE@#The effects of the staurosporine on contraction of self-assembled constructs and extracellular matrix syntheses of goat temporomandibular joint discs were investigated.@*METHODS@#Goat temporomandibular joint disc cells were isolated and cultured to P3, and 5.5×10⁶ cells were combined with different concentrations of staurosporine (0, 0.1, 1, 10, 100 nmol·L⁻¹) in agarose wells and cultured for one week. The samples were frozen and sectioned. Safranin-O,  Picro-sirius red and immunohistochemical staining were performed to observe the distributions of the extracellular matrix and the expression of alpha-smooth muscle actin (α-SMA). Enzyme linked immunosorbent assay (ELISA) and Blyscan kits were utilized to quan--titatively detect the contents of type Ⅰ collagen (ColⅠ) and glycosaminoglycans (GAGs).@*RESULTS@#Each group of goat temporo-mandibular joint disc cells in the agarose wells were gathered to self-assemble into a disc-shaped base for 4 hours and then to gradually contract into a round shape. The Picro-sirius red staining was strong and indicated collagen distribution. The Safranin-O staining observed GAGs throughout the entire construct. The expression of ColⅠ was strongly posi-tive in the staurosporine groups; however, the expression of α-SMA was weak. ColⅠ and GAGs contents in the stau-rosporine groups were greater than that of the control group, especially in the 10 nmol·L⁻¹ group (P<0.01).@*CONCLUSIONS@#Staurosporine has a certain effect on the shrinkage of self-assembled constructs; however, such effect is not prominent. Staurosporine contributes to the construction synthesis of extracellular matrix.

Manejo quirúrgico para los desarreglos internos de la articulación temporomandibular una alternativa con resultados promisorios / Surgical management for internal derangement of the temporomandibular joint an alternative with promising results

Objetivo. Describir las características clínicas y quirúrgicas de un grupo de pacientes con diagnóstico de disfunción de articulación temporomandibular (ATM) llevados a manejo quirúrgico. Diseño del estudio: Se realizó un estudio observacional descriptivo. Materiales y métodos: Se evaluaron las características clínicas y quirúrgicas de un grupo de pacientes con disfunción de ATM llevados a manejo quirúrgico con un periodo de seguimiento de uno y tres meses en el servicio de cirugía maxilofacial del Hospital de San José de Bogotá. Se incluyeron 110 articulaciones a las cuales se les realizó una o varias de las siguientes cirugías: meniscopéxia, eminectomía y condilectomía. Se realizó estadística descriptiva utilizando medidas de tendencia central, de dispersión, frecuencias absolutas y relativas. Resultados. La mayoría de los pacientes con síntomas clínicos tuvieron hallazgos anormales en resonancia magnética. El 90,6% y el 91% de los pacientes presentaron ausencia de dolor y ruido articular respectivamente. De igual forma se evidenció mejoría en la movilidad de la mandíbula. Conclusión. La cirugía para los desarreglos internos de la ATM es una cirugía segura con resultados muy favorables en nuestra población.

Objective: To describe the clinical and surgical characteristics of a group of patients with Temporomandibular joint (TMJ) disorder who underwent surgical intervention. Study design: Descriptive observational study Methods: A group of patients with TMJ disorders who underwent surgical intervention at department of Otolaryngology and Maxillofacial Surgery Hospital de San Jose were evaluated. They were followed during the first and third month post intervention. 110 temporomandibular joints were included. The procedures included one or more of the following: meniscopexy, eminectomy, and/or condilectomy. A descriptive analysis was done using central tendency and dispersion measures, as well as relative and absolute frequencies. Results: A great number of patients with clinical manifestations had abnormal findings in the magnetic resonance (MRI). 90,6% of patients presented pain relief and 91% absence of joint sounds. In addition, there was recovery of the normal mobility of the mandible. Conclusion: Surgical intervention for the internal derangement of the TMJ, is safe and had favorable results in the studied population.

Metrical analysis of disc-condyle relation with different splint treatment positions in patients with TMJ disc displacement

Abstract Objective: To evaluate the effect of bite positions characterizing different splint treatments (anterior repositioning and stabilization splints) on the disc-condyle relation in patients with TMJ disc displacement with reduction (DDwR), using magnetic resonance imaging (MRI). Material and Methods: 37 patients, with a mean age of 18.8±4.3 years (7 male and 30 females) and diagnosed with DDwR based on the RDC/TMD, were recruited. MRI metrical analysis of the spatial changes of the disc/condyle, as well as their relationships, was done in three positions: maximum intercuspation (Position 1), anterior repositioning splint position (Position 2), and stabilization splint position (Position 3). Disc/condyle coordinate measurements and disc condyle angles were determined and compared. Results: In Position 1, the average disc-condyle angle was 53.4° in the 60 joints with DDwR, while it was −13.3° with Position 2 and 30.1° with Position 3. The frequency of successful "disc recapture" with Position 2 was significantly higher (58/60, 96.7%) than Position 3 (20/60, 33.3%). In Positions 2 and 3, the condyle moved forward and downward while the disc moved backward. The movements were, however, more remarkable with Position 2. Conclusions: Anterior repositioning of the mandible improves the spatial relationship between the disc and condyle in patients with DDwR. In addition to anterior and inferior movement of the condyle, transitory posterior movement of the disc also occurred.

Distribution of stress on TMJ disc induced by use of chincup therapy: assessment by the finite element method

ABSTRACT Objective: To assess the distribution of stress produced on TMJ disc by chincup therapy, by means of the finite element method. Methods: a simplified three-dimensional TMJ disc model was developed by using Rhinoceros 3D software, and exported to ANSYS software. A 4.9N load was applied on the inferior surface of the model at inclinations of 30, 40, and 50 degrees to the mandibular plane (GoMe). ANSYS was used to analyze stress distribution on the TMJ disc for the different angulations, by means of finite element method. Results: The results showed that the tensile and compressive stresses concentrations were higher on the inferior surface of the model. More presence of tensile stress was found in the middle-anterior region of the model and its location was not altered in the three directions of load application. There was more presence of compressive stress in the middle and mid-posterior regions, but when a 50o inclined load was applied, concentration in the middle region was prevalent. Tensile and compressive stresses intensities progressively diminished as the load was more vertically applied. Conclusions: stress induced by the chincup therapy is mainly located on the inferior surface of the model. Loads at greater angles to the mandibular plane produced distribution of stresses with lower intensity and a concentration of compressive stresses in the middle region. The simplified three-dimensional model proved useful for assessing the distribution of stresses on the TMJ disc induced by the chincup therapy.

RESUMO Objetivo: avaliar, por meio do método dos elementos finitos, a distribuição das tensões no disco articular produzidas pela mentoneira ortopédica. Métodos: um modelo tridimensional simplificado do disco articular foi desenvolvido com o software Rhinoceros 3D e exportado para o software ANSYS. Uma carga de 4,9 N (500 gf) foi aplicada na superfície inferior do modelo, com inclinação de 30, 40 e 50o em relação ao plano mandibular Gônio-Mentoniano (GoMe). O ANSYS analisou, por meio do método dos elementos finitos, a distribuição das tensões presentes no modelo do disco articular para as diferentes angulações. Resultados: os resultados mostraram que a concentração das tensões de tração e compressão foi maior na superfície inferior do modelo. A tensão de tração foi mais presente na região média-anterior do modelo, e sua localização não se alterou nas três direções da aplicação da carga. A tensão de compressão foi mais presente nas regiões média e média-posterior do modelo, mas quando a carga a 50o foi aplicada, ela se concentrou na região média. As intensidades das tensões de tração e compressão diminuíram progressivamente à medida que a carga foi aplicada mais verticalmente. Conclusão: as tensões induzidas pela mentoneira ortopédica se localizaram principalmente na superfície inferior do modelo. As cargas com maior angulação em relação ao plano mandibular produziram uma distribuição de tensões com menor intensidade e uma concentração da tensão de compressão na região média do modelo. Um modelo tridimensional simplificado se mostrou útil na avaliação da distribuição das tensões no disco articular induzidas pela mentoneira ortopédica.