RESUMO
We report a case of exclusive involvement of lymph node in leishmaniasis presenting as generalized lymphadenopathy. The diagnosis of lymphatic leishmaniasis was confirmed by the presence of Leishmania donovani body in fine needle aspiration cytology, positive direct agglutination test and anti-rK39 antibodies. The bone marrow aspiration was negative for Leishmania donovani body. This is the first case of lymphatic leishmaniasis reported from Nepal.
Assuntos
Adulto , Animais , Feminino , Humanos , Leishmania donovani/isolamento & purificação , Leishmaniose Visceral/diagnóstico , Doenças Linfáticas/parasitologia , NepalRESUMO
As lymphadenopathy is probably the most common finding in the acquired toxoplasmosis. To analyze the site and character of enlarged lymph nodes in seropositive cases of toxoplasmosis. SETTING: Department of microbiology, BMSI, JPMC, Karachi. MATERIAL AND METHODS: A total of 100 individuals of different age and sex groups having lymphadenopathy were included in the study for antitoxoplasma IgG and IgM antibody levels. Relevant information was recorded on a proforma. lymph nodes of the neck region were maximally involved i.e. 88.34%. Majority of the involved nodes were discrete, mobile, smooth in texture and firm in consistency. Half of the patients had tender lymph nodes. Among the other clinical features, fever was the most common presenting symptom [61.11%]. t 20[55.56%] of 36 positive cases were having contact with animals, contact with cats was maximum i.e. 75%
Assuntos
Humanos , Masculino , Feminino , Doenças Linfáticas/parasitologia , Linfonodos/parasitologia , Toxoplasma/patogenicidadeRESUMO
Em dois pacientes, com suspeita clínica de linfoma ou escrofuloderma - por apresentarem linfadenopatias cervicais importantes -, o estudo dos linfonodos removidos para exame histológico revelou um processo necrótico-granulomatoso e a presença de leishmanias (amastigotas) no interior de macrófagos. Lesöes cutâneas mucosas, características da leishamniose tegumentar americana, näo foram percebidas, embora um dos pacientes viesse posteriormente a desenvolvê-las, como provável efeito de tratamento para toxoplasmose. O achado fundamenta a suspeita de que os agentes da doença, após penetrarem no organismo do hospedeiro, podem alojar-se em órgäos do sistema monocítico-fagocitário, aí permanecendo durante muito tempo, talvez mesmo por toda a vida do indivíduo infectado. Eventualmente, sob a açäo de fatores diversos, capazes de afetar a resistência do hospedeiro, migrariam os parasitos para a pele ou as mucosas, determinando lesöes secundárias ou de reativaçäo