Hallazgos de imagen en tomografia computada de voluntarios fumadores de larga data / Findings on computed tomography imaging of long-standing volunteer smokers

The finding of pulmonary nodules in computed tomography is extremely common, with a reported prevalence ranging between 8 percent and 51 percent in volunteers, usually around 25 percent. Of these, about 2 percent to 13 percent are malignant nodules. Age, medical records of extra thoracic cancer existing 5 years before nodule detection, spiculated edges, big size, upper location and a recorded history of tobacco consumption are major risk factors for malignancy. Among these, smoking is one of the most common, with a known increased risk of malignancy (Odds ratio= 2.2). Working with the hypothesis that in smokers a higher prevalence of lesions is expected when compared to the normal population, we conducted a thoracic computed tomography study in 239 volunteers over 38 years (103 men and 135 women), who had been consuming more than 15 cigarettes a day over more than 10 years. Data were analyzed with statistical parametric and multivariate analyses. Some types of lesions were found in 82.5 percent of men and in 87.4 percent of women, being lung (53.7 percent) and mediastinal (13.8 percent) injuries the most frequent ones. Among these, bulls, scars, mediastinal lymphadenopathy and nodules constituted the main lesions (between 21.4 percent and 44.7 percent of the injuries). Nodules accounted for 21.4 percent of lesions in men and 25.2 percent in women, which falls within the normal range as described in volunteers. The cluster analysis, applied in conjunction with Jaccard coefficient of association, showed that nodules do not exist in isolation but in conjunction with other signs, forming a cluster that contains bulls, nodules, scars, mediastinal lymphadenopathy, aortic calcifications, and pleural thickening. Among lesions of potential oncological relevance, an overall finding of 5.83 percent in men and 4.44 percent in women is documented. Solitary nodules were found in 12 males and in 29 females, of whom 7 (58.3 percent) and 10 (34.5 percent), respectively...

El hallazgo de nodulos pulmonares en tomografía computada es extremadamente común, habiéndose reportado prevalencias entre 8 y 51 por ciento en voluntarios, habitualmente alrededor de 25 por ciento; de éstos, 2 a 13 por ciento serían malignos. La edad, antecedente de cáncer extratorácico más de 5 años antes del nodulo, bordes espiculados, gran tamaño, localizador superior y antecedente de consumo de cigarrillos son los principales factores de riesgo de malignidad. El cigarrillo es uno de los más comunes, con conocido aumento del riesgo (Odds ratio= 2.2). Trabajando con la hipótesis que en fumadores se espera mayor prevalencia de lesiones que en la población normal, estudiamos con tomografía computada de tórax 239 voluntarios mayores de 38 años (103 hombres, 135 mujeres), consumidores de más de 15 cigarrillos diarios por más de 10 años. Se analizaron los datos con estadística paramétrica habitual y multivariada. Encontramos 82,5 por ciento hombres y 87,4 por ciento mujeres con alguna lesión; las más frecuentes: pulmonares (53,7 por ciento) y mediastínicas (13,8 por ciento); las principales: bulas, cicatrices, adenopatías mediastínicas y nodulos (21,4 a 44,7 por ciento de las lesiones). Los nodulos correspondieron a 21,4 por ciento de las lesiones en hombres y 25,2 por ciento en mujeres, en rango habitual para lo descrito en voluntarios. El análisis de conglomerados con índice de asociación Jaccard mostró: los nodulos no se presentan aislados, evidenciándose un conglomerado que contiene: bulas, nodulos, cicatrices, adenopatías mediastínicas, calcificaciones aórticas y engrosamiento pleural. Entre las lesiones de posible importancia oncológica destacan: 5,83 por ciento en hombres y 4,44 por ciento en mujeres; 12 nodulos solitarios en hombres y 29 en mujeres, de los cuales 7 (6,8 por ciento) y 10 (7,4 por ciento) constituirían indicaciones de acciones diagnóstico-terapéuticas de mayor agresividad.

Estudio comparativo de la cirugía torácica no cardíaca en pacientes menores y mayores de 60 años / Comparative study of thoracic surgery in patients under and over 60

Nos propusimos hacer un estudio comparativo, en los Hospitales Universitarios Joaquín Albarrán Domínguez y General Calixto García Iñiguez, para comparar los resultados inmediatos de la cirugía torácica no cardíaca en pacientes menores y mayores de 60 años, en un período de 7 años (1996 a 2002). Evaluamos la totalidad de los pacientes intervenidos quirúrgicamente por enfermedades torácicas no cardíacas, y tomamos en cuenta las conductas preoperatorias, transoperatorias y posoperatorias, así como la evolución del paciente y su estado al egreso. Encontramos predominio de los pacientes menores de 60 años, entre los cuales prevalecieron los del sexo femenino, y no ocurrió así entre los mayores de 60 años, grupo en el cual predominó el sexo masculino. En general, los pacientes mayores de 60 años eran más saludables, pues se registró en este grupo el mayor porcentaje de personas sin antecedentes patológicos o factores de riesgo. Los diagnósticos que más frecuentemente motivaron la intervención quirúrgica fueron el cáncer de pulmón y el de esófago. Paradójicamente, hubo un mayor porcentaje de complicaciones y de fallecimientos entre los pacientes menores de 60 años(AU)

A comparative study was made at Joaquín Albarrán Domínguez and General Calixto García Iñiguez hospitals to compare the inmediate results of noncardiac thoracic surgery in patients under and over 60 in a period of 7 years (1996 to 2002). All the patients that underwent surgery due to noncardiac thoracic diseases were evaluated, and the preoperative, transoperative and postoperative behaviors, as well as the patient’s evolution and their state on discharge, were taken into consideration. It was found a predominance of patients under 60 , among whom females prevailed; whereas those over 60 were mostly males. Generally, patients over 60 were healthier, since in this group, most of the patients had neither pathogical history nor risk factors. The diagnoses that led more frequently to surgery were lung and esophagus cancer. Paradoxically, a higher percentage of complications and deaths was observed among patients under 60(AU)

Analysis of status of surgery in thoracic tuberculosis.

A retrospective analysis of the surgical procedure in 1655 patients in twenty years in a university hospital for thoracic tuberculosis revealed that the varieties of procedures were necessary in 2.2% cases only. They can be grouped as tubercular empyema with or without bronchopleural fistula in 1507 (91%), complicated pulmonary tuberculosis in 78 (4.7%), cold abscess in the chest wall with or without lymphadenitis in 54 (3.2%) and osteomyelitis of the ribs and sternum in 16 cases (0.9%). This is statistically significant with a confidence interval of 0.1248 to 0.2348. In tubercular empyema 222 procedures were performed of which 162 were minor procedures, intercostal drainage with irrigation: 89 cases, thoracostoma: 56 cases and continuous chest wall tube 17 cases and 60 were major procedures (decortication in 45 cases, thoracoplasty [modified] in 14 cases and muscle transfer in one case). All the above procedures were preceded by an intercostal drainage. In complicated pulmonary tuberculosis the operative procedures were as follows: lobectomy in 33 cases, pneumonectomy in 35 cases and thoracoplasty in 10 cases. Drainage of cold abscess with or without lymphnode resection was performed in 54 cases and in 16 cases of osteomyelitis of the ribs and sternum resection were necessary. All procedures were performed under the cover of antitubercular therapy and supportive treatment with the aim of resolution of process, obliteration of the empyema space, control of sepsis and improvement of activity performance. The morbidity was extensive and mortality was high in major procedures. Good results could be obtained in over 92% cases, and only 66.2% on major surgery cases.