Fonsecaea pedrosoi as a rare cause of acute conjunctival ulceration / Fonsecaea pedrosoi como agente raramente associado à úlcera conjuntival aguda

ABSTRACT Conjunctival ulceration accompanied with secretion and pain was observed in a 30-year-old male, 3 days after a perforating corneal trauma. Cultures of conjunctival ulcer samples grew Fonsecaea pedrosoi, a major causative agent of chromoblastomycosis that is typically transmitted during trauma. The conjunctival ulcer was successfully treated with amphotericin B, itraconazole, and fluconazole. This case report summarizes the diagnosis and treatment of a conjunctival ulcer due to F. pedrosoi, which is a rare complication of contaminated ocular trauma. To the best of our knowledge, this is the first reported case of F. pedrosoi causing acute conjunctival ulceration in the literature.

RESUMO O quadro clínico de uma úlcera conjuntival acompanhada de secreção e dor foi observado em homem de 30 anos de idade, 3 dias após um trauma perfurante da córnea. As culturas de uma amostra retirada da úlcera conjuntival foi positiva para Fonsecaea pedrosoi, uma cromoblastomicose, geralmente transmitido após traumatismos. O caso foi tratado com sucesso com a anfotericina B, itraconazol e fluconazol. Este relato de caso reporta o diagnóstico e tratamento de uma úlcera conjuntival causada por F. pedrosoi, que raramente é visto nos olhos expostos a traumatismos contaminados. Até onde sabemos, este é o primeiro caso relatado na literatura de F. pedrosoi causando úlcera conjuntival aguda.

Disseminated cutaneous sporotrichosis associated with ocular lesion in an immunocompetent patient

Abstract: A 59-year-old female patient, previously healthy, immunocompetent, presented left bulbar conjunctiva lesions and nodular-ulcerated lesions on the arms and cervical region, besides left cervical and retroauricular lymphadenopathy. She had previous contact with domestic cats that excoriated her face. The diagnosis was conclusive of disseminated sporotrichosis through clinical and epidemiological history and cultures of skin and ocular secretions. It evolved with good response to oral antifungal therapy.

Microbiological efficacy of lomefloxacin and other drugs regarding microorganisms isolated from the human conjunctiva

Purpose: To evaluate and compare the in vitro susceptibility of human conjunctival bacterial isolates to various antimicrobial agents, including lomefloxacin, other fluoroquinolones (ciprofloxacin, norfloxacin, and ofloxacin), aminoglycosides (gentamicin, tobramycin, and amicacin), and cephalosporin ( cephalothin). Methods: Antibiotic susceptibility tests conducted over a period of 27 months with 613 bacterial isolates from the conjunctiva were retrospectively analyzed.Results to the total number of positive isolates, the fluoroquinolones showed greater in vitro effectiveness than the other analyzed antibiotics. All bacterial isolates showed significantly higher susceptibility to ciprofloxacin than to lomefloxacin. Conclusion: the fluoroquinolones are not only equally effective against all conjunctival bacterial isolates but they also show superior antimicrobial activity in comparison to aminoglycosides and cephalothin. These results suggest that fluoroquinolones, such as lomefloxacin, can be beneficially prescribed for conjunctival infections and also as prophylaxis in ocular surgery.

Microbiota fúngica conjuntival: estudo comparativo entre pacientes com AIDS, pacientes infectados pelo HIV e pacientes HIV-negativos antes da era do HAART / Fungal microbiota: comparative study between patients with acquired immuno-deficiency syndrome, patients infected with human immunodeficieny virus and immunocompetent individuals before the HAART era

Foi pesquiasda a presença de fungos na conjuntiva ocular de 23 pacientes com AIDS, 24 pacientes infectados pelo HIV, ambos de controle ambulatoraial e 48 indivíduos HIV negativos, durante um ano, nos meses de fevereiro, abril, julho e outubro. O fungo mais isolado foi Penicillium sp, seguido de Aspergillus sp, Candida sp e Rhodotorula sp. Embora sem diferença significante, em todas as coletas foi verificados um crescimento maior de fungos na conjuntiva dos portadores de AIDS, seguido pelo grupo infectado pelo HIV e em menor número nos individuos HIV-negativos

Complicaciones nasofaríngeas de la conjutivitis folicular por chalmydia trachomatis. Una causa de la falta de respuesta al tratamiento / Nasopharingeal complications secundary to Clamydia trachomatis follicular conjunctivitis. A cause of therapeutic failure

Se realizó un estudio retrospectivo en 6 409 casos consecutivos en un lapso de enero de 1992 a febrero de 1997, se seleccionaron 183 frotis nasales y 271 faríngeos provenientes de 396 pacientes. Chlamydia trachomatis fue el agente etiológico en el 67.80 por ciento de los frotis nasales y 8.11 por ciento de las muestras faríngeas. La infección nasal es casi siempre secundaria a la infección ocular y a su vez es un factor de diseminación y de falta de respuesta adecuada al tratamiento, por lo que es indispensable identificar el problema y dar tratamiento simultáneo