Characterization and clinical application of mesenchymal stem cells from equine umbilical cord blood

Tendinitis of the superficial digital flexor tendon (SDFT) is a significant cause of lameness in horses; however, recent studies have shown that stem cells could be useful in veterinary regenerative medicine. Therefore, we isolated and characterized equine umbilical cord blood mesenchymal stem cells (eUCB-MSCs) from equine umbilical cord blood obtained from thoroughbred mares during the foaling period. Horses that had tendinitis of the SDFT were treated with eUCB-MSCs to confirm the therapeutic effect. After eUCB-MSCs transplantation, the core lesion in the SDFT was found to decrease. These results suggest that transplantation using eUCB-MSCs could be another source of cell treatment.

Modificaçöes na técnica de correçäo cirúrgica de dilaceraçäo perineal de 3§ grau em éguas / Modifications of surgical correction of the 3rd degree perineal laceration in mares

Em 52 éguas de diferentes raças e idades, praticou-se cirurgia corretiva de dilaceraçäo perineal de 3§ grau, com modificaçöes na técnica de GOTZE, na tentativa de restabelecer a anatomia do sistema reprodutor, bem como a vida reprodutiva destas fêmeas. Das éguas que sofreram a cirurgia, a totalidade (100//) retornou à reproduçäo, alcançando-se o índice máximo de fertilidade após inseminaçäo artificial ou cobertura. Os resultados obtidos pelo emprego da técnica proposta permite indicá-la como uma conduta correta e eficiente na recuperaçäo anátomo-funcional do genital de éguas com dilaceraçäo de períneo de 3§ grau