RESUMO
Elephantiasis nostras verrucosa, a rare manifestation of Kaposi's sarcoma, is a progressive cutaneous hypertrophy caused by chronic non-filarial lymphedema secondary to obstruction of the lymphatic system that can lead to severe disfigurement of parts of the body that have gravity-dependent blood flow, due to edema, fibrosis, and hyperkeratosis, especially lower extremities. Among the various conditions that can induce chronic lymphedema are tumors, trauma, radiotherapy, obesity, hypothyroidism, chronic venous stasis, and AIDS-related Kaposi's sarcoma. Kaposi's sarcoma is a vascular tumor associated with the presence of human gammaherpesvirus 8 that is predominantly cutaneous, locally aggressive, with metastasis, and is associated with the production of factors that favor inflammation, lymphatic obstruction, and lymphedema.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Sarcoma de Kaposi/complicações , Infecções Oportunistas Relacionadas com a AIDS/complicações , Elefantíase/diagnóstico , Sarcoma de Kaposi/patologia , Sarcoma de Kaposi/tratamento farmacológico , Didanosina/uso terapêutico , Infecções Oportunistas Relacionadas com a AIDS/patologia , Infecções Oportunistas Relacionadas com a AIDS/tratamento farmacológico , Lamivudina/uso terapêutico , Fármacos Anti-HIV/uso terapêutico , Ciclopropanos , Benzoxazinas/uso terapêutico , Quimioterapia Combinada , Elefantíase/etiologia , Elefantíase/patologia , AlcinosRESUMO
Demonstra-se quadro raro de Elefantíase Nostra, na sua forma verrucosa, no dorso de pé de homem de 80 anos por episódios prévios de erisipela de repetição. As lesões confluentes vegetantes e difusas em dorso de pé são comparáveis aos corais Trumpet Coral (Caulastrea curvata).
Study of a rare case of Elephantiasis Nostra in verrucous form on the dorsum of the foot of an 80year-old male with a history of recurrent erysipelas infection. The vegetant, confluent lesions on the foot resemble Trumpet Coral (Caulastrea curvata).
Assuntos
Idoso de 80 Anos ou mais , Humanos , Masculino , Elefantíase/etiologia , Erisipela/complicações , Dermatoses do Pé/etiologia , Doença Crônica , Elefantíase/patologia , Dermatoses do Pé/patologiaRESUMO
Grave's disease is an autoimmune disease of thyroid gland and pretibial myxedema occurs in 4% of these patients. We present a 50-year-old man with Grave's disease who was referred with nonpitting, edematous, erythematous plaques on legs and feet that became elephantiasic. Biopsy of skin revealed granular material deposition in dermis with splitting of collagen fibers. This is a rare presentation of pretibial myxedema that presented in this case