Effect of dietary salt (NaCl) supplementation on urinary profile of guinea pigs (Cavia porcellus).

Sodium chloride supplementation (120 mg/kg of body weight/day) for 12 days increased the urinary excretion of calcium from 91.6 +/- 9.0 to 159.4 +/- 16.0 mumol/day and of sulphate from 266.8 +/- 24.5 to 1176.9 +/- 87.2 mumol/day in guinea pigs. The stone risk due to increased urinary calcium excretion could possibly be counterbalanced by increasing urinary sulphate excretion. High salt intake, thus, could not increase the risk of stone formation.

Indican, ethereal and other forms of S eliminated in 24 hours urine by elderly Indian subjects.

Average daily excretion of Indican in urine of 42 healthy elderly men, av. age 69.9 +/- 5.0 years, (60 observations) was 60.7 +/- 17.4 mg/24 hrs. This is slightly higher than reported values for younger subjects. Average ethereal S elimination by Indian subjects has varied from 72-150 mg/day. Indican is the chief ethereal S eliminated in urine. Other forms of S excreted by elderly subjects were: Inorganic S 720 +/- 150 mg; Ethereal S 74 +/- 22 mg. Indican in them was 53.8 +/- 17.4 mg. This shows that the remaining 20 mg or about 1/4 of the ethereal S is eliminated in urine in other forms. Relationship with age, diet, common disorders along with findings in literature etc. are discussed.

Influence of dietary energy and protein on the urinary excretion of nitrogen and sulfur

Twenty-five males aged 24 to 28 years were considered for the study. Urinary creatinine, total nitrogen, sulfate sulfur, nitrogen/creatinine ratio, sulfate sulfur/nitrogen ratio and the sulfate sulfur/creatinine ratio were determined. The dietary data has suggested a deficiency of calories available to the subjects. The 24-hour output of total nitrogen, sulfate sulfur and all the three biochemical ratios increased as the dietary energy level declined significantly but the protein intake remained the same. However, the values of all the biochemical parameters concerned decreased as the dietary protein level declined significantly but the energy intake was somewhat similar. From the results of this investigation it also appears that the sulfate sulfur/creatinine ratio is a better index of utilizable protein for the subjects than the nitrogen/creatinine ratio

Nitrogen and sulphur elimination in 24 hours urine by elderly Indians.

Urinary output of N2-urea, creatinine, uric acid, ammonia and organic and inorganic SO3 were repeatedly examined in healthy vegetarian subjects in Bombay--35 elderly and 2 young. Their routine diet examined for a week indicated an average intake of 56 g proteins (15 g animal) and excretion of about 8 g N2, 0.75 g of SO3 both in young and old subjects. These are much lower than figures reported for Europeans taking protein rich diets. Two elderly subjects supplemented their protein intake to 95 g/day (50 g animal) for 3 weeks. A progressive rise in the outputs of N2 and SO3 with increasing protein intakes was seen. SO3 estimation like that of N2 (urea) is indicative of the protein consumption of a person, but the estimations of urea output per day being easier are to be preferred.