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1.
Acta cir. bras ; 33(12): 1103-1109, Dec. 2018. tab
Artigo em Inglês | LILACS | ID: biblio-973490

RESUMO

Abstract Purpose: To evaluate a possible relationship between the size of the spleen and values of circulating blood elements in patients with schistosomatic splenomegaly. Methods: ixty one patients with hepatosplenic schistosomiasis mansoni underwent a clinical exam and peripheral venous blood was collected for a hemogram. The erythrocyte, hemoglobin, hematocrit, leukocyte, and platelet values were determined. All patients underwent abdominal ultrasound to measure the spleen. The hematological test results were compared to the size of the spleen. Results: The size of the spleen varied from 14.0 to 28.4 (19.9 ± 3.7) cm according to the ultrasound image. Thrombocytopenia was observed 58 (95%) patients, leukopenia in 55 (90%) patients, and anemia in 32 (52.4%) patients. Leukopenia was proportional to splenomegaly. Conclusion: Schistosomal splenomegaly leads to leukopenia in direct proportion to the size of the spleen.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Baço/patologia , Esplenomegalia/patologia , Esplenomegalia/sangue , Esquistossomose mansoni/patologia , Esquistossomose mansoni/sangue , Tamanho do Órgão , Valores de Referência , Baço/parasitologia , Esplenomegalia/parasitologia , Trombocitopenia/parasitologia , Contagem de Células Sanguíneas , Estatura , Peso Corporal , Hemoglobinas/análise , Índice de Massa Corporal , Leucopenia/parasitologia
2.
Rev. Inst. Med. Trop. Säo Paulo ; 41(4): 235-8, July-Aug. 1999.
Artigo em Inglês | LILACS | ID: lil-246832

RESUMO

We studied 12 Hb C carriers: 4 homozygotic Hb CC and 8 heterozygotic. We observed the presence of free crystals in the peripheral blood of the homozygotes but in none of the heterozygotes. However, after incubation with 3 percent NaCl we were able to detect crystals in the heterozygotes (Hb AC and Hb SC), and in the homozygotes (Hb CC). In patient 04 (P04) less crystals formation occurred due to inhibition of the process by the presence of elevated levels of Hb F (12.2 percent). All the homozygotic patients had a splenomegaly of 3 to 6 fingerbreadths.We believe that the spleen wears off with time, thus allowing the passage of crystals to the peripheral blood. This finding might be associated with splenic insufficiency without a reduction of its dimensions. Finally, the finding of crystals in the peripheral blood permitted the diagnosis of Hb C obviating the need for electrophoresis


Assuntos
Humanos , Doença da Hemoglobina C/diagnóstico , Hemoglobina C/química , Esplenomegalia/sangue , Cristalização , Eletroforese em Gel de Ágar , Homozigoto , Baço/fisiopatologia
4.
Egyptian Journal of Schistosomiasis and Infectious and Endemic Diseases. 1994; 16 (1): 37-52
em Inglês | IMEMR | ID: emr-32188
6.
Braz. j. med. biol. res ; 25(11): 1091-102, 1992. ilus, tab
Artigo em Inglês | LILACS | ID: lil-134604

RESUMO

1. The plasma concentrations of low- and high-density lipoproteins (LDL and HDL) were significantly reduced in Brazilian patients with compensated hepatosplenic schistosomiasis mansoni (SM) when compared with healthy individuals, but very low-density lipoprotein (VLDL) levels were unchanged. 2. All three classes of lipoproteins isolated from SM plasma had an increased content of triacylglycerol and unesterified cholesterol and decreased cholesteryl ester and phospholipid. 3. The individual phospholipid composition of patient VLDL, LDL, HDL was also altered; the amount of phosphatidylcholine was increased and that of lysophosphatidylcholine decreased. 4. The saturated and monounsaturated fatty acyl content of cholesteryl esters in patient lipoproteins was also significantly increased, and diunsaturated and polyunsaturated fatty acyl content was decreased. 5. When isolated lipoproteins were examined as negatively stained preparations by electron microscopy, the morphology of SM patient LDL was normal but the HDL fraction was abnormal and showed marked heterogeneity of size with the presence of occasional discoidal particles which resembled nascent HDL


Assuntos
Humanos , Masculino , Feminino , Hepatomegalia/sangue , Lipídeos/sangue , Lipoproteínas HDL/sangue , Lipoproteínas LDL/sangue , Lipoproteínas VLDL/sangue , Esquistossomose mansoni/sangue , Esplenomegalia/sangue , Adulto , Brasil , Cromatografia em Camada Fina , Lipoproteínas HDL/ultraestrutura , Lipoproteínas LDL/ultraestrutura , Lipoproteínas VLDL/ultraestrutura , Microscopia Eletrônica
7.
Indian J Pediatr ; 1991 Sep-Oct; 58(5): 679-81
Artigo em Inglês | IMSEAR | ID: sea-81296
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