Plasma factor XIII in patients with diabetic angiopathy

Plasma factor XIII was estimated in 30 diabetic patients with angiopathy and in 10 healthy individuals with matched age and sex as a control group. There was a highly significant increase in factor XIII activity in plasma of diabetic patients which might promote intravascular and endoparietal fibrin deposition and may contribute to the development of atherosclerotic complications. Fasting blood sugar, age of the patient, duration of the disease had no influence on factor XIII activity