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Indian J Exp Biol ; 2007 May; 45(5): 469-74
Artigo em Inglês | IMSEAR | ID: sea-61979

RESUMO

Cadmium (Cd) is one of the environmental contaminant and because of its non-decomposable character, it can damage nature. In this study, TEM was used in order to assess the ultrastructural effects of Cd on photorececptor and ganglionic cells of mouse retinal layer. Apoptotic nuclei, heterochromatic nuclei, deletion of nucleus membrane, invisible nucleolus, and apoptotic cells with mitochondrial changes were observed in mice embryo (days 15 of gestation) following CdCl2 injection to mothers on day 9 of gestation. Cadmium exposure caused apoptotic changes both in photoreceptors and ganglionic cells.


Assuntos
Animais , Apoptose/efeitos dos fármacos , Cádmio/toxicidade , Núcleo Celular/efeitos dos fármacos , Feminino , Gânglios Sensitivos/efeitos dos fármacos , Masculino , Camundongos , Camundongos Endogâmicos BALB C , Retina/efeitos dos fármacos
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