RESUMO
Epithelioid Hemangioendothelioma is a rare vascular tumor of low malignant potential most commonly found in the lung, liver and soft tissues. Penis is a very rare site for it. We report a case of penile epithelioid hemangioendothelioma. Surgery is the standard treatment and close clinical follow up is necessary due to its unpredictable natural history.
Assuntos
Adulto , Hemangioendotelioma Epitelioide/complicações , Hemangioendotelioma Epitelioide/epidemiologia , Hemangioendotelioma Epitelioide/cirurgia , Humanos , Seguimentos , Masculino , Doenças do Pênis/epidemiologia , Doenças do Pênis/etiologia , Doenças do Pênis/cirurgia , PênisRESUMO
Epithelioid hemangioendothelioma is a rare vascular tumor, which occurs in the lung, liver, bone, and soft tissue. Hypertrophic osteoarthropathy is a syndrome characterized by subperiosteal new bone formation, joint effusion and clubbing, and may be associated with cyanotic heart disease, chronic pulmonary disease, liver disease, and other miscellaneous diseases. The activation of endothelium and platelets has been suggested to be involved in the development of hypertrophic osteoarthropathy. We report a rare case of hypertrophic osteoarthropathy, which developed in association with hepatic epithelioid hemangioendothelioma with pulmonary metastasis. We also discuss the role of vascular endothelial growth factor in its pathogenesis.
Assuntos
Adulto , Humanos , Masculino , Biópsia , Plaquetas/metabolismo , Endotélio/metabolismo , Fêmur/diagnóstico por imagem , Hemangioendotelioma Epitelioide/complicações , Pulmão/patologia , Neoplasias Pulmonares/complicações , Osteoartropatia Hipertrófica Secundária/complicações , Fator A de Crescimento do Endotélio Vascular/metabolismo , Neoplasias Vasculares/diagnósticoRESUMO
Pulmonary epithelioid hemangioendothelioma (PEH) is an uncommon neoplasm. The reported case reveals unusual clinical manifestations pericardial effusion and raised CA-125 level.