RESUMO
Focal nodular hyperplasia (FNH) is a benign condition of the liver often discovered incidentally on radiological investigation. Although FNH is a well-described lesion in the literature considerable diagnostic problems regarding this entity still remains. We report a case of multiple FNH in a 23-year-old male patient detected as an incidental finding in autopsy. On gross examination FNH was not suspected because of the multiple lesions and the lack of central scar which is characteristically described in FNH. The diagnosis was established on histopathology after examination of multiple sections of the lesions.
Assuntos
Autopsia , Hiperplasia Nodular Focal do Fígado/diagnóstico , Hiperplasia Nodular Focal do Fígado/patologia , Histocitoquímica , Humanos , Achados Incidentais , Fígado/patologia , Masculino , Microscopia , Reticulina/análise , Nitrato de Prata , Coloração e Rotulagem/métodos , Adulto JovemRESUMO
Focal Nodular Hyperplasia is a benign lesion of the liver, which usually presents with one or two localizations. We report the uncommon case of a 51-year-old female who presents with right upper quadrant pain that worsened in the previous month, without association with feeding. Four hepatic lesions were evidenced at Computerized tomography, the largest being of 8 cm in diameter, of atypical behavior. She was submitted to hepatic segmentectomy of the segment III. The pathologic diagnosis returned focal nodular hyperplasia mixed hyperplastic and adenomatous sub-type. The patient had a good postoperative evolution and is in ambulatory follow-up.
Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Hiperplasia Nodular Focal do Fígado/patologia , Adenoma/patologia , Hiperplasia Nodular Focal do Fígado/classificaçãoRESUMO
No abstract available.
Assuntos
Adulto , Humanos , Masculino , Meios de Contraste , Hiperplasia Nodular Focal do Fígado/patologia , Fígado/patologia , Imageamento por Ressonância Magnética , Tomografia Computadorizada por Raios XRESUMO
Fibrolamellar hepatocellular carcinoma (FLC) is a rare histologic variant of hepatocellular carcinoma that appears most commonly in teenagers and young adults. The diagnosis is often made incidentally and surgical resection is the only curative treatment. Here we report two cases of incidental FLC involving a 19 year-old male, initially diagnosed with screening abdominal ultrasound, and a 14 year-old female that presented with abdominal pain. Diagnostic workup consisted of abdominal PET/CT and MRI Imaging studies and tissue diagnosis was confirmed with percutaneous liver biopsy. Both patients were treated with radical liver resection/tumor excision. However, tumor recurrence was observed in both during short-term follow-up. The male patient was treated successfully with surgical treatment however the female patient succumbed top regression of disease.
Assuntos
Adolescente , Feminino , Humanos , Masculino , Adulto Jovem , Carcinoma Hepatocelular/cirurgia , Neoplasias Hepáticas/cirurgia , Biópsia , Carcinoma Hepatocelular/patologia , Evolução Fatal , Hiperplasia Nodular Focal do Fígado/patologia , Hiperplasia Nodular Focal do Fígado/cirurgia , Neoplasias Hepáticas/patologia , Linfonodos/patologia , Recidiva Local de Neoplasia , Tomografia Computadorizada por Raios X , Adulto JovemRESUMO
An 8-year-old boy was admitted because of recurrent fever for 1 month with increased CRP and ESR. Ultrasound reviewed multiple, small, hypo-echoic, rounded and wedge-shaped nodules with diffuse blood flow in spleen and enlarged abdominal lymph nodes. The spleen was enlarged and no echoic space was found in the largest lesion on 5th day. After a positive mycoplasma pneumoniae (MP) IgM was reported on 6th day, azithromycin was used intravenously. The temperature returned to normal and CRP and ESR improved in a short period. The lesions and lymphadenopathy disappeared and MP IgM antibody became negative 6 months later.
Assuntos
Antibacterianos/uso terapêutico , Azitromicina/uso terapêutico , Sedimentação Sanguínea , Proteína C-Reativa/análise , Criança , Hiperplasia Nodular Focal do Fígado/patologia , Humanos , Imunoglobulina M/análise , Masculino , Pneumonia por Mycoplasma/sangue , Baço/patologia , Esplenopatias/patologia , Tomografia Computadorizada por Raios XRESUMO
No abstract available.
Assuntos
Adulto , Feminino , Humanos , Hiperplasia Nodular Focal do Fígado/patologiaRESUMO
Nodular regenerative hyperplasia of the liver [NRHL] is characterized by hepatocellular nodules without fibrous septa between the nodules, and has been described in association with certain diseases. The NHRL should be considered in a liver mass and coexisting portal hypertension. We described the case of a 33-year-old Iranian man with NRHL in association with essential thrombocythemia