1.
Artigo
em Inglês
| IMSEAR
| ID: sea-16495
2.
Southeast Asian J Trop Med Public Health
; 1977 Mar; 8(1): 80-3
Artigo
em Inglês
| IMSEAR
| ID: sea-36341
RESUMO
Twenty-four hour urinary histamine in 12 patients with DHF compared to 12 normal subjects in the comparable age and sex were studied. The results revealed significantly increased urinary excretion in patients with DHF than in normal subjects in both free and total forms. This finding suggests that histamine may be one, if not all, of the mediators released during the course of the disease, especially in the severe cases. Histamine may play an important role for the leakage of intravascular fluid to the various serous spaces resulting in hypovolemia and shock.