Clinical and histological patterns of dermatofibroma without gross skin surface change: A comparative study with conventional dermatofibroma.

Backg round: Dermatofibroma sometimes clinically presents as a nodular lesion without gross skin surface change. Clinicopathologic features of this variant of dermatofi broma have not been evaluated. Aims: To assess clinicopathologic features of dermatofi broma presenting as a subcutaneous nodule. Methods: This study reviewed the clinical and histological features of 42 cases of subcutaneous dermatofibromas and compared them with 95 cases of conventional dermatofi broma. Results: Dermatofi broma without gross skin surface change was associated with a shorter pre-diagnosis duration than conventional dermatofi broma. Increase in size during the pre-diagnosis period was signifi cantly more frequent in the conventional type. In addition, these dermatofi bromas were more likely than the conventional type to occur in the head and neck region. Although tumor depth was deeper than in the conventional type, less than half of the dermatofi bromas without gross skin surface change were found histologically to be “subcutaneous” or “deep-penetrating dermatofi broma”. Subcutaneous extension was more frequent in these dermatofi bromas while focal stromal hyalinization and hemosiderin deposits were more common in the conventional type. Limitations: This study is a retrospective, single center design. Conclusion: The present study suggests that dermatofi broma without gross skin surface change is a variant type with distinct clinical and histological features that distinguish them from conventional dermatofi broma.

Benign fibrous histiocytoma of the maxilla: A case report and review of literature.

Benign fibrous histiocytoma (BFH) is a mesenchymal tumor which commonly affects the skin of extremities. Histologically, BFH of soft tissues and bone shows similar features, but BFH of the bone is rare with less than 100 cases reported worldwide and usually it involves tibia, femur, and pelvic bone. As far as the oral cavity is concerned, majority of the BFHs are found in the soft tissues of the buccal mucosa, gingiva, lower and upper lips, soft palate, and floor of the mouth. Occurrence of this tumor in the jaw bones is extremely rare as only one case of the maxilla and six cases of the mandible have been reported so far . Hence, the purpose of this article is to report the second case of BFH of the maxilla in a 23-year-old female patient and to review the literature of this entity affecting the jaws.

Tumours and tumour-like lesions of bone. The UHWI experience. University Hospital of the West Indies

A review of all primary tumours and tumour-like lesions of bone diagnosed in patients who attended the University Hospital of the West Indies over a 10-year period revealed 136 cases comprising 69 benign and 54 malignant tumours, and 13 cases of tumour-like lesions. The prevalence and clinical characteristics of the various lesions are discussed and compared with the findings in other series. The results of this analysis provide demographic data useful in the differential diagnosis of bone lesions locally.

Dermatofibroma, frecuencia en un servicio de patología quirúrgica / Dermatofibroma, frecuency in a service surgical pathology

Se informa de 103 casos de dermatofibroma diagnósticados en el Departamento de Anatomía Patológica del Hospital General de Zona Núm 14 del Instituto Mexicano del Seguro Social en Guadalajara, Jalisco, estudiados en el periodo comprendido entre 1986 y 1995. Los datos obtenidos fueron analizados estadísticamente y se consideraron porcentajes, tasas, proporciones, media y desviación estándar. El tumor afectó principalmente a mujeres jovenes (71..8 por ciento), la edad promedio fue de 35 años; en 65.8 por ciento se localizó en extremidades y su prevalencia fue 2.66 por 100,000 derechohabientes

Tumores óseos. Estadística en relación a sexo, edad y sitio. Informe de 1351 casos / Bone tumors. Statistic in relationship to sex, age and location. Report of 1351 cases

Se presenta una serie de 1351 casos de tumores óseos primarios benignos y malignos, metastásicos, tumores malignos de tejidos blancos que invadieron hueso y lesiones seudotumorales atendidos en ocho años, de 1982 a 1989 en el Hospital de Ortopedia Magdalena de las Salinas del IMSS. La relación del sexo masculino y femenino fue de 1.3:1; la población pediátrica correspondió a 422 pacientes, de los cuales 91.5% cursaron con lesiones malignas y 8.5% con tumores malignos; 929 enfermos fueron adultos, y de ellos, 75.6% tuvieron lesiones benignas y 24.4% tumores malignos. Los segmentos anatómicos afectados con mayor frecuencia fueron: la extremidad pélvida con 754 casos y la extremidad torácica con 301. Se presenta el registro detallado en las variables analizadas. Los datos encontrados en nuestro estudio son similares a los informacos en las "series clásicas".