RESUMO
Abstract Intravascular histiocytosis is a rare condition characterized by the aggregate of histiocytes within dilated dermal vessels. The diagnosis is mainly histophatological and immunohistochemical. We describe a case of a 55 year-old female patient presenting erythematous/purple patches on the breasts, back and limbs. She previously presented ductal carcinoma in the right breast in 2006 which was treated with mastectomy and proceeded to silicone breast implant in 2009. Clinical hypothesis was telangiectatic metastatic carcinoma. Histopathology showed vascular ectasia, thrombosis and recanalization of upper dermis small vessels. On immunohistochemistry, intravascular cells were CD 68+ and negative for estrogen and progesterone receptors, CK7, EMA and AE1/AE3 and endothelial cells were CD64+, leading to the diagnosis of intravascular histiocytosis.
Assuntos
Humanos , Feminino , Silicones/efeitos adversos , Histiocitose/etiologia , Histiocitose/patologia , Dermatopatias Vasculares/etiologia , Dermatopatias Vasculares/patologia , Implante Mamário/efeitos adversos , Imuno-Histoquímica , Trombose Venosa/etiologia , Trombose Venosa/patologia , Dilatação Patológica , Pessoa de Meia-IdadeRESUMO
La enfermedad de Rosai-Dorfman, o sinuhistiocitosis con linfadenopatía masiva, es una rara patología que se presenta con linfadenopatía dolorosa generalizada, más frecuentemente en cabeza y cuello. Su curso clínico y tratamiento es variable. Se describe el caso de un paciente masculino con compromiso nasal de la enfermedad...
Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy, is a rare disorder presented as painless bilateral lymph node enlargement mainly in the head and neck region. Clinical course and treatment regimen are variable. We described one male patient with nasal involment...