RESUMO
Neonatal septicaemia is a major cause of morbidity and mortality in developing countries. We studied 118 neonates admitted to the main referral hospital in Al-Anbar with positive blood cultures. The incidence of neonatal septicaemia for babies born at this hospital was 9.2 per 1000 live births, and mortality was 28%. Staphylococcus aureus [39%], Klebsiella pneumoniae [30%] and Escherichia coli [21%] constituted 90% of all isolates. The isolates showed in vitro susceptibility to cefotaxime, chloramphenicol and gentamicin, but resistance to more commonly used antibiotics such as ampicillin and cloxacillin. We recommend initial gentamicin/cefotaxime combined therapy while awaiting culture and sensitivity test results. Our study highlights the importance of understanding the local epidemiology of neonatal septicaemia in formulating a rational antibiotics policy
Assuntos
Feminino , Humanos , Bacteriemia/congênito , Cefotaxima , Farmacorresistência Bacteriana , Infecções por Escherichia coli/congênito , Gentamicinas , Mortalidade Hospitalar , Incidência , Infecções por Klebsiella/congênito , Klebsiella pneumoniae , Testes de Sensibilidade Microbiana , Infecções Estafilocócicas/congênito , Staphylococcus aureusRESUMO
Empyema thoracis, a serious complication of pneumonia, fortunately remains a less common cause of respiratory distress in neonates. Only 14 cases of neonatal empyema thoracis have been described in the world literature. The condition is characterized by its rarity, inability to identify any consistent predisposing factors, uncertain pathogenesis, rapid course, lack of consensus on management and a high mortality. We describe here two cases of empyema aged 6 and 8 days caused by E. Coli and Klebsiella respectively. Out of them one survived. A brief review of literature follows the above account.