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EDJ-Egyptian Dental Journal. 1993; 39 (3): 491-494
em Inglês | IMEMR | ID: emr-27618

RESUMO

45 male albino rats were used to study the effect of deep submucosal implantation of DMBA on lingual carcinogenesis. The results showed development of different mesenchymal neoplasm [fibroma, fibrosarcoma and leiomyosarcoma]. So, this method of implantation could not be used as an ideal animal model for production of single known neoplasm as had been investigated by many investigators before


Assuntos
Animais de Laboratório , Neoplasias da Língua/induzido quimicamente , Mesoderma/efeitos dos fármacos , Ratos , Fibroma/induzido quimicamente , Fibrossarcoma/induzido quimicamente , Leiomiossarcoma/induzido quimicamente
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