Pulmonary malakoplakia: A report of two cases.

Malakoplakia of lung is an unusual condition that has been reported to occur in association with immunocompromised state, particularly in those with acquired immunodeficiency syndrome. We present two cases of pulmonary malakoplakia in immunocompetent individuals. The diagnosis was made on histopathological examination of surgically resected specimen.

Malacoplaquia intestinal / Colonic malakoplakia

Malacoplakia is a chronic granulomatous disease of unknown origin. However immunodeficiency states (immunossuppressive medication, old people, renal transplantation, leukaemia, diabetes mellitus, malnutrition and others) have been associated with patients with malacoplakia. An infectious cause of malakiplakia is suggested by the finding of coliform bacteria in the phagolysosomes of macrophages. The histologic study is characterized by a infiltrate of large macrophages (Hansenmann cells) with pathognomonic inclusions containing siderocalcific structures (Michaelis-Gutmann bodies). Most of the cases reported in literature, involve the genitourinary tract, but other structures can be affected (brain, bone, adrenal glands, lymph nodes, intestine, and others). A 66-year-old man whith a abdominal mass, went to our hospital with a colonic tumour diagnosis. The patient was submitted to a surgery, with resection of the rigth colon. The disease was invading a portion of the retroperitoneal tissue that was removed. The histopatologic study showed the pathognomonic sign of malakoplakia (Hansenmann cells and Michaelis-Gutmann bodies). Norfloxacin have been used to the complementar treatment with total cure of the patient

Malacoplasia do intestino grosso, bexiga e retroperitônio: relato de caso / Malacoplakia of large bowel, bladder and retroperitoneum: report of a case

Os autores relatam um caso de malacoplasia acometendo o intestino grosso, bexiga e retropertônio, doença rara, principalmente pelo comprometimento de mais de um órgäo. Trata-se do segundo caso observado em nosso Serviço, envolvendo os mesmos órgäos. Estudam os meios diagnósticos e terapêuticos e däo ênfase à associaçäo sulfametoxazol-trimetoprim (SMZ-TM) e ácido ascórbico, que se mostrou eficiente a longo prazo na resoluçäo da enfermidade

Malacoplasia vesical / Malacoplakia of the bladder

Apresenta-se um caso de malacoplasia vesical, tendo sido realizada cirurgia como conduta terapêutica, com bons resultados