Synthesis of some heterocyclic compounds containing naphthalene nucleus for biological evaluation

In this work, 2 mercapto-4-aryl-4H-1,2,3,4,5,6- hexahydrobenzo[h]quianazolines [1] were condensed with alkyl halide to yield the alkyl derivatives II. 3-chloro acetylacetone condensed with compound I in pyridine to yield the thiazoloquinazolines derivatives III. The aminopyrimidine derivatives V were prepared by condensation of aryl methylene-1-tetralone with guanidine hydrochloride. Alpha- tetralone condensed with malononitrile in ethyl alcohol in the presence of beta-alanine to yield 1,2,3,4-tetrahydronaphtho-alpha- yiledene malononitrile VII. Compound VII added one mole of aromatic aldehyde in ethanol in presence of potassium hydroxide to yield 2-imino-10-aryl-8,9-dihyronaphtho[1,2-d] pyrano-3-carhonitrile VIII. Compounds VIII were reacted with ammonium acetate in acetic acid to yield 2-amino-10-aryl-3,9-dihydronaphtho[l,2-d]-3-carbonitrile IX. Compounds IX were prepared directly from VII by the action of appropriate aromatic aldehyde and ammonium acetate in acetic acid

Synthesis and characterization of mono and binuclear cobalt [II], nicked [II] and copper [II] complexes with N2O2-schiff bases of diamino-naphthalenes

Mono and binuclear cobalt [II], nickel [II] and copper [II] complexes containing quadridentate Schiff bases were prepared and characterized by elemental analysis, 1R, electronic and epr spectra. The complexes were subjected to TGA, conductance and electrical resistivity measurements. The observed resistivities of the complexes at different temperatures follow the order Co [II]