RESUMO
Despite advances in health care, morbidity and mortality associated with acute renal failure [ARF] remain high. This study determined the frequency and etiology of ARF in hospitalized patients in Saudi Arabia over 2 years. Of the 150 cases of ARF, 38.0% were community-acquired and 62.0% hospital-acquired. The main cause was acute tubular necrosis [ATN] in 93 patients, due to sepsis [24.7%], ischaemia [12.7%], rhabdomyolysis [mainly from road traffic accidents] [10.7%], drugs [7.3%] and malaria and snake-bites [4.6%]. Overall, 40% died, 48% made a full recovery and 1 patient [0.7%] became dialysis-dependant. Factors associated with poor prognosis were: age 60+ years, community-acquired ARF, peak blood urea nitrogen > 160 mg/dL, duration of ARF > 1 week, need for dialysis and associated chronic liver disease
Assuntos
Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Distribuição por Idade , Causas de Morte , Pacientes Internados/estatística & dados numéricos , Isquemia/complicações , Necrose do Córtex Renal/complicações , Hepatopatias/complicações , Malária/complicações , Morbidade , Análise Multivariada , Preparações Farmacêuticas/efeitos adversos , Prognóstico , Diálise Renal , Rabdomiólise/complicaçõesRESUMO
Se informa un caso de necrosis cortical renal, que se diagnosticó en el Hospital Escuela. Esta patología no es común. Tradicionalmente asociada a condiciones de embarazo. Sin embargo, ahora se le atribuyen a la sépsis, venenos de serpientes, quimioterapia, drogas o efectos secundarios de medicamentos, como las causas más frecuentes. Es todavía una condición médica que tiene un alto porcentaje de mortalidad y que presenta varias limitaciones para su diagnóstico temprano
Assuntos
Humanos , Feminino , Adulto , Insuficiência Renal/etiologia , Necrose do Córtex Renal/cirurgia , Necrose do Córtex Renal/complicações , Necrose do Córtex Renal/diagnósticoRESUMO
Of 63 patients of obstetrical acute renal failure, 15 cases (23.8%) had biopsy proven bilateral renal cortical necrosis. Remaining 48 patients (76.2%) had acute tubular necrosis. Eight of 39 cases in early pregnancy had cortical necrosis (postabortum) and 7 of 24 patients in late pregnancy revealed cortical necrosis. Diffuse and patchy cortical necroses were seen in 12 and 3 patients respectively. The incidence of cortical necrosis was almost equal in both early as well as late pregnancies. The high incidence (20.5%) of cortical necrosis following septic abortion remains the interesting feature of the present study in contrast to very low incidence (1.5%) of cortical necrosis in postabortum group in developed countries. The death occurred in most patients (14 ie, 93.3%) of cortical necrosis because of uraemic complications and sepsis.