RESUMO
Abstract Infantile hemangioma is the most common pediatric vascular tumor, with the following risk factors: low birth weight, prematurity, white skin, female gender, multiparity and advanced maternal age. The use of oral and topical beta-blockers, although recent, has emerged as the first line of treatment, with superior safety and efficacy to previously used therapies, such as corticosteroids and surgeries. This report describes two cases of nasal tip infantile hemangioma, treated with oral propranolol. Both presented excellent therapeutic responses.
Assuntos
Humanos , Feminino , Lactente , Propranolol/administração & dosagem , Neoplasias Nasais/tratamento farmacológico , Antagonistas Adrenérgicos beta/administração & dosagem , Hemangioma/tratamento farmacológico , Neoplasias Nasais/patologia , Administração Oral , Resultado do Tratamento , Hemangioma/patologiaRESUMO
Abstract Nasal type extranodal NK/T-cell lymphoma is a distinct entity according to the World Health Organization classification. Although 60% to 90% of patients with this disease present with a destructive mass in the midline facial tissues, it may also primarily or secondarily involve extranasal sites, like the skin. We report the case of a 77-year-old patient that came to our department with erythematous plaques of the right leg and eczematous lesions of the trunk. These lesions were biopsied and the patient was diagnosed with extranodal NK/T-cell lymphoma, nasal type. He was treated with multi-agent systemic chemotherapy but died 5 months after diagnosis. This case highlights the rarity and variability of cutaneous features of this disease and its aggressive course and poor prognosis.
Assuntos
Humanos , Masculino , Idoso , Neoplasias Cutâneas/patologia , Neoplasias Nasais/patologia , Linfoma Extranodal de Células T-NK/patologia , Neoplasias Primárias Múltiplas/patologia , Pele/patologia , Neoplasias Cutâneas/tratamento farmacológico , Vincristina/uso terapêutico , Biópsia , Prednisona/uso terapêutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Doxorrubicina/uso terapêutico , Neoplasias Nasais/tratamento farmacológico , Evolução Fatal , Ciclofosfamida/uso terapêutico , Linfoma Extranodal de Células T-NK/tratamento farmacológico , Neoplasias Primárias Múltiplas/tratamento farmacológicoRESUMO
Se presenta el caso de un paciente, mestizo masculino de 39 años de edad, que es visto en consulta por sangramiento nasal. Al examen físico se detecta masa tumoral que ocupa la fosa nasal izquierda. Se toma muestra para biopsia informándose la presencia de un cordoma de localización nasal. Se realizan complementarios correspondientes y se indica terapéutica oportuna...