Metástasis de adenocarcinoma de recto al conducto auditivo externo: presentación de un caso y revisión de la literatura / Metastatic rectal adenocarcinoma to the external auditory canal: case report and literature review

Las metástasis de neoplasias primarias de diferentes localizaciones a cabeza y cuello son un hecho infrecuente. La localización más habitual de recepción de dichas metástasis es el hueso temporal, sitio que usualmente es afectado por neoplasias que se diseminan a los huesos en general. Sin embargo, las neoplasias al conducto auditivo externo son muy raras, habiéndose publicado pocos casos en la literatura . Presentamos el caso de un varón de 81 años con clínica de dolor, acúfenos y otorrea derecha. La otomicroscopía demostró una lesión polipoide en el conducto auditivo extemo derecho. La biopsia objetivó una proliferación de células epiteliales atípicas que formaban luces glandulares anómalas con positividad para citoqueratina 20 y antígeno carcinoembrionario. Se diagnosticó como metástasis de adenocarcinoma de probable origen colónico y posteriormente se conocieron antecedentes de colectomía 9 años antes por adenocarcinoma de recto-sigma. Las metástasis de adenocarcinoma de colon al conducto auditivo externo son un hecho infrecuente y de aparición tardía. Requieren un diagnóstico diferencial con metástasis de adenocarcinomas de otras localizaciones y, en menor medida debido a su baja frecuencia, con tumores primarios. Entre estos últimos, los que plantean mayores dificultades diagnósticas son los adenocarcinomas ceruminosos.

Metastasis to the head and neck region are unusual. The most common site of receiving those metastasis is the temporal bone, a site which is usually affected by tumors that spread to the bones. However, metástasis to the external auditory canal are infrequent. Only a few cases have been published in the literature. We report the case of a 81 year-old man with pain, tinnitus and right otorrhea. The otomicroscopy showed a polypoid lesion in the right ear canal. The biopsy showed an atypical proliferation of epitelial cells forming anomalous glands, which were positive for citoqueratine 20 and carcinoembryonic antigen. He was diagnosed with metastatic adenocarcinoma of colon-rectum nine years previously Metastasis of colon adenocarcinomas to the external auditory canal are infrequent. Require a defferential diagnosis with metastatic adenocarcinomas of others locations but is always necessary to rule outprimary tumors. Among these, the most challenging diagnostic is with ceruminous adenocarcinomas.

Solitary Metastasis of Bronchogenic Adenocarcinoma to the Internal Auditory Canal: A Case Report

We report a patient with an isolated metastasis to the internal auditory canal (IAC) of bronchogenic adenocarcinoma. A 58-yr-old man who had received 6-cycle of chemotherapy under diagnosis of non-small cell lung carcinoma (T4N2M0) two years ago was referred to our department with vertigo, right-sided facial paralysis and right-sided hearing loss. A provisional diagnosis of vestibular schwannoma or meningioma involving right IAC was made from magnetic resonance imaging. The patient underwent a translabyrinthine removal of the tumor. Histopathological study of the resected lesion showed a poorly differentiated adenocarcinoma compatible with bronchogenic origin. The patient died 9 months after surgery from extensive brain metastasis despite postoperative radiation therapy. In patients with a previous history of treatment of malignancy elsewhere in the body, the possibility of IAC metastasis must be considered when an IAC lesion is detected.

An atypical presentation of recurrent temporal lobe meningioma with external auditory canal mass.

Extracranial spread of recurrent meningiomas involving the middle ear is rare. We present the case of a 59-year-old woman with headache and swelling of scalp over the right temporal region. MRI revealed a lesion in the right temporal lobe suggestive of meningioma. She underwent complete surgical excision of the lesion followed by post-operative radiotherapy. After 1 year, she presented with right-sided otalgia and a middle-ear mass extruding into the external auditory canal. She was re-operated and histopathology was anaplastic meningioma. We are discussing this unusual pattern of recurrence in our patient with a review of literature.