Bacterial susceptibility and resistance analysis of traumatic osteomyelitis

With the rapid development of industry, agriculture and transportation, the high energy trauma happened accordingly, thus greatly increased the incidence of traumatic osteomyelitis. The clinical traumatic osteomyelitis was mainly the local bone tissue inflammation caused by bacteria infection as trauma or iatrogenic causes. The delaying recovery could cause bone defection or bone nonunion. The purpose of this paper was to contribute new reference for the clinical prevention and treatment through tremendous of disease-causing bacteria susceptibility and resistance analysis of osteomyelitis

Bisphosphonate associated osteomyelitis of the jaw in patients with bony exposure: prevention, a new way of thinking

Objective There is strong evidence of a link between the use of systemic bisphosphonates (BPs) and osteonecrosis of the jaw, especially in cancer patients. Among risk factors for BRONJ, tooth extraction and immune suppressive drugs seem to have significant role on bone healing. Therefore, the importance of these parameters in development of BRONJ was reviewed in this retrospective study in two maxillofacial surgery units. Material and Methods From 2007 to 2012, 46 patients on bisphosphonate who had developed oral bony lesions participated in this study. The pharmacological exposure, comorbidities, maxillofacial findings, types of treatment and outcome data were collected from clinical and radiological records. Results The most frequently used BP was alendronate (67%). Tooth extraction was reported in 61% of patients with BRONJ. Systemic corticosteroids were prescribed in 35 cases (76%) as an adjuvant for BP. Patients on corticosteroids had a lower probability of bony lesion healing (p<0.05) than patients without corticosteroids. Of the 46 patients who underwent conservative treatments, only ten were completely healed (21%). Conclusions Beside tooth extraction, corticosteroids were shown to be an implant risk factor for low rate of bone healing and hence the development of BRONJ. The outcome of conservative treatment was uncertain and this emphasizes the importance of prevention. .

Prevençäo e tratamento das osteomielites pós-traumáticas dos membros inferiores com retalhos musculares / Prevention and treatment of post-traumatic osteomyelites of the lower leg using muscle flaps

No presente trabalho säo discutidos os métodos de tratamento das lesöes tegumentares pós-traumáticas dos membros inferiores através de transposiçöes musculares e enxertos de pele, associados à reparaçäo óssea. Cinquenta e seis pacientes foram estudados no Serviço de Cirurgia Plástica e Microcirurgia Reconstrutiva da Santa Casa de Misericórdia de Porto Alegre, no período de julho de 1992 a julho de 1994. A localizaçäo mais frequente dos ferimentos foi no terço médio da perna (35,7 por cento dos casos). Setenta e cinco por cento dos pacientes tiveram como causa principal do traumatismo o envolvimento em acidente de motocicleta ou de automóvel. Cinquenta e seis pacientes (83,5 por cento) foram tratados com a transposiçäo de retalhos musculares pediculados, sendo o músculo Sóleo o mais empregado no método (50 por cento dos retalhos). Houve resoluçäo da infecçäo e estabilizaçäo dos ferimentos em 80,6 por cento dos casos. Salienta-se a importância fundamental de uma abordagem interdisciplinar e atuaçäo precoce para o sucesso do tratamento