Assuntos
Humanos , Feminino , Adulto , Artrite Reumatoide/tratamento farmacológico , Estomatite/induzido quimicamente , Metotrexato/efeitos adversos , Antirreumáticos/efeitos adversos , Mucosite/induzido quimicamente , Overdose de Drogas/complicações , Estomatite/patologia , Metotrexato/administração & dosagem , Toxidermias/etiologia , Toxidermias/patologia , Antirreumáticos/administração & dosagem , Mucosite/patologia , Overdose de Drogas/patologia , NecroseRESUMO
Paraquat, a dipyridium compound is widely used as a herbicide. It is available in India as a liquid concentrate for agricultural use and is highly toxic if ingested. It leads to renal, hepatic, cardiac and pulmonary toxicity and also causes burns of oral mucosa and esophagus as it is caustic in nature. We describe two cases of paraquat poisoning who developed serious toxicity following its ingestion and died of respiratory failure.
Assuntos
Adulto , Evolução Fatal , Feminino , Herbicidas/intoxicação , Humanos , Pulmão/patologia , Overdose de Drogas/patologia , Paraquat/intoxicação , Síndrome do Desconforto Respiratório/induzido quimicamente , SuicídioRESUMO
A total of thirty cases of aluminium phosphide poisoning were studied for gross and microscopic changes in various organs of the body ie, lungs, liver, kidneys, heart, brain, stomach and adrenals. The histopathological changes revealed varying degrees of congestion, oedema and leucocytic infiltration, changes suggestive of cellular hypoxia. The most dramatic effects were produced in lungs, kidneys and adrenals.