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1.
Rev. bras. ginecol. obstet ; 37(1): 16-23, 01/2015. tab
Artigo em Português | LILACS | ID: lil-732876

RESUMO

OBJETIVO: Avaliar o hábito alimentar e nutricional de mulheres na pós-menopausa e compará-los com o perfil antropométrico, faixa etária e tempo de menopausa. MÉTODOS: No período de junho a agosto de 2011, 148 mulheres na pós-menopausa residentes no Estado de São Paulo (região Sudeste do Brasil) foram avaliadas com um questionário estruturado contendo dados socioeconômicos, clínicos, antropométricos e alimentares. Avaliou-se nível de atividade física, variáveis bioquímicas, Índice de Massa Corporal (IMC), circunferência abdominal (CA) e consumo alimentar (energia, proteínas, carboidratos e gorduras, fibra, colesterol, vitaminas A e C, minerais, cálcio e ferro) de acordo com a faixa etária e o tempo de pós-menopausa (TPM). RESULTADOS: A média de IMC foi 29,0±5,6 kg/m2 e da CA, 95,7±12,9 cm. O consumo médio calórico diário atingiu 1.406,3±476,5 kcal. A ingestão e a adequação calórica foram significantemente mais apropriadas entre as mulheres eutróficas e com CA<88 cm. O mesmo ocorreu quanto ao consumo de proteínas (p<0,001 e p=0,006, respectivamente). Na análise por faixa etária ou TPM não houve diferenças significantes, exceto a média do consumo proteico, maior no grupo com 5 anos ou menos de menopausa (p=0,048). CONCLUSÃO: O perfil antropométrico de mulheres na pós-menopausa mostrou predominância de sobrepeso ou obesidade. O consumo alimentar apresentou-se adequado quanto às calorias e percentuais de macronutrientes, entre as eutróficas e com CA<88 cm. .


PURPOSE: To evaluate eating in postmenopausal women and its relation to anthropometry, age and time since menopause in São Bernardo do Campo residents. METHODS: During the period from June to August of 2011, 148 postmenopausal women residents in state of São Paulo (Southeast region of Brazil) were evaluated using a structured questionnaire containing socioeconomic, clinical, anthropometric and food data. The level of physical activity, biochemical variables, Body Mass Index (BMI), abdominal circumference (AC) and dietary intake (energy, protein, carbohydrates and fats, fiber, cholesterol, vitamins A and C, minerals, calcium and iron) were analyzed according to age and time after menopause. RESULTS: Mean BMI was 29.0≤5.6 kg/m2 and abdominal circumference was 95.7±12.9 cm. The average daily caloric consumption was 1,406.3±476.5 kcal. The calorie intake was significantly more appropriate in normal-weight women and women with AC<88 cm. The same was observed for protein intake (p<0.001 and p=0.006, respectively). No association was observed with age or duration of the postmenopausal period, except for average protein consumption that was higher in the group with five years or less of menopause (p=0.048). CONCLUSION: The anthropometry of postmenopausal women showed a predominance of overweight and obesity. Dietary intake was adequate in relation to the percentage of calories and macronutrients and calories among most normal-weight women and women with AC<88 cm. .


Assuntos
Humanos , Antineoplásicos/uso terapêutico , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Citocinas/biossíntese , Floxuridina/uso terapêutico , Picibanil/uso terapêutico , Neoplasias Gástricas/tratamento farmacológico , Timidina Fosforilase/biossíntese , Antineoplásicos/administração & dosagem , Indução Enzimática , Floxuridina/administração & dosagem , Gastrectomia , Expressão Gênica , Interleucina-1/biossíntese , Invasividade Neoplásica , Estadiamento de Neoplasias , Picibanil/administração & dosagem , Neoplasias Gástricas/patologia , Neoplasias Gástricas/fisiopatologia , Neoplasias Gástricas/cirurgia , Estômago/patologia , Fator de Necrose Tumoral alfa/biossíntese
2.
Rev. chil. pediatr ; 85(6): 714-719, dic. 2014. ilus
Artigo em Espanhol | LILACS | ID: lil-734813

RESUMO

Lymphangiomas are a common form of vascular malformation of the lymphatic vessels, mainly in the head and neck region. Most cases are progressive evolution and require a multidisciplinary approach. Currently, the first therapeutic option is sclerotherapy, leaving surgery for the treatment of remaining lesions. Objective: To present a case of facial lymphatic malformation (LM) treated with sclerotherapy, surgery and orthodontics in a 15-year follow up. Case report: A one-year-old female patient who consulted health professionals due to a progressive volume increase of the soft parts of her right cheek. The imaging study confirmed the diagnosis of microcystic lymphatic malformation. It was managed with OK-432 sclerotherapy and Bleomycin. At 2 years of age, the patient response was considered adequate; an intralesional submandibular surgical excision was then performed, with partial resection of the lesion. The biopsy confirmed the diagnosis of microcystic LM. Six months after, a re-resection was planned using the same approach and removing the remaining lesion, with favorable development until the age of 9 years when the patient required surgery and orthodontic management due to intraoral recurrence. No major developments until the age of 13 when a new orthodontic surgery and handling are planned to perform right oral commissure suspension. Conclusion: LM management by sclerotherapy, surgery, and orthodontics has shown the advantages of a multidisciplinary long-term treatment in this case.


El linfangioma corresponde a una malformación vascular de los vasos linfáticos, preferentemente de la región de cabeza y cuello. La mayoría de los casos son de evolución progresiva y requieren un manejo multidisciplinario. Actualmente la primera opción terapéutica es la esclerosis, reservando la cirugía para el tratamiento de las lesiones remanentes. Objetivo: Presentar un caso de malformación linfática (ML) facial, tratado con escleroterapia, cirugía y ortodoncia en un seguimiento a 15 años. Caso clínico: Paciente de sexo femenino que consulta al año de edad por aumento de volumen progresivo de partes blandas en su mejilla derecha. El estudio de imágenes confirmó el diagnóstico de Malformación Linfática microquística. Se manejó con esclerosis seriada con OK-432 y Bleomicina. A los 2 años de edad se consideró que la respuesta era adecuada, y se procedió a realizar extirpación quirúrgica intralesional submandibular, con resección parcial de la lesión. La biopsia confirmó el diagnóstico de ML microquística. Seis meses después se planificó nueva resección utilizando el mismo abordaje y extirpando lesión remanente, con evolución favorable hasta la edad de 9 años en que requiere cirugía y manejo por ortodoncia, por recidiva de lesión a nivel intraoral. Evolución favorable hasta que a la edad de 13 años se planifica nueva cirugía y manejo por ortodoncia para suspender la comisura bucal derecha. Conclusión: El manejo de la ML mediante escleroterapia, cirugía, y ortodoncia muestra en este caso las ventajas de un tratamiento multidisciplinarion a largo plazo.


Assuntos
Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Neoplasias Faciais/terapia , Linfangioma/terapia , Anormalidades Linfáticas/terapia , Escleroterapia/métodos , Bleomicina/administração & dosagem , Seguimentos , Neoplasias Faciais/diagnóstico , Neoplasias Faciais/patologia , Linfangioma/diagnóstico , Linfangioma/patologia , Anormalidades Linfáticas/diagnóstico , Anormalidades Linfáticas/patologia , Ortodontia Corretiva/métodos , Picibanil/administração & dosagem
3.
Artigo em Inglês | IMSEAR | ID: sea-46450

RESUMO

OBJECTIVE: The basic objective of this study was to find out the efficacy of OK-432 for the conservative treatment of lymphangiomas of head and neck regions at the Department of ENT-Head & Neck Surgery of Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal. METHODS: It was a hospital based prospective, cross-sectional, case series, conducted among the patients suffering from different lymphangiomas of head and neck regions and treated with intra-lesional injection of OK-432, from March, 2005 to September 2006. Altogether eleven patients were enrolled in this modality of treatment out of which one patient was excluded from the study, which was treated surgically due to very ugly scar at the site of lesion resulting from previous surgery for the same. The data were analyzed by using simple mathematical tools like percentage and frequency. RESULTS: Out of ten patients treated with intralesional injection of OK-432, absolute response, i.e. total resolution of swelling was found in nine patients (90%) after the first dose. Remaining one patient also responded well on the treatment but some residual swelling was in situ for which second dose was given. After the second dose it was also totally resolved. In this way we achieved 100% response after the second dose of OK-432. CONCLUSION: The results of this study so far indicate that OK-432 is an effective and safe tool for the treatment of lymphangioma of head and neck region. As the procedure can be done in an out patient department, without hospitalization and has got minimal side effects, it can be proposed as the first line treatment of lymphangiomas of head and neck.


Assuntos
Adolescente , Adulto , Criança , Pré-Escolar , Estudos Transversais , Feminino , Neoplasias de Cabeça e Pescoço/terapia , Humanos , Lactente , Injeções Intralesionais , Masculino , Picibanil/administração & dosagem , Estudos Prospectivos , Soluções Esclerosantes/administração & dosagem , Resultado do Tratamento
4.
Rev. cir. infant ; 8(3): 145-8, sept. 1998. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-238029

RESUMO

Fue realizada una inyección intralesional de OK-432(una preparación con incubación liofilizada de streptococos pyogenes de origen humano)en 7 pacientes con linfangioma lingual bajo anestesia general, a intervalos de 6 semanas. Un paciente mostró una disminución marcada del volúmen del linfangioma con apariencia normal de la lengua y sin complicaciones relacionadas con el tratamiento. En los 6 pacientes restantes fue notada en 5 una disminución parcial del tamaño de la lesión, y en 1 no hubo respuesta.De los 5 pacientes con reducción parcial, en 4 se realizó una resección en cuña de la lesión para reducir el tamaño de la lengua obteniéndose excelente resultado en uno, bueno en 2 y regular en 1. Todos mostraban una mordida anormal antes de la reducción quirúrgica. Después de la reducción, uno mostró mordida completamente normal y 2 una mejoría en la misma. La terapia con OK-432 fue útil para el tratamiento del linfangioma cavernoso de la lengua y permitió la realización de una resección en cuña para reducir el tamaño de la lengua afectada, con baja incidencia de...


Assuntos
Humanos , Criança , Picibanil/administração & dosagem , Neoplasias da Língua/diagnóstico , Neoplasias da Língua/tratamento farmacológico
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