RESUMO
Pilomatrixoma is an uncommon adnexal tumor with heterogeneous features can mimic various malignancies and contributes to false positive diagnosis on cytology. It is an uncommon, slow growing, benign skin adnexal neoplasm of hair matrix origin initially described by Malherbe and Chenantais. This tumor is predominantly found in the head and neck region, and presents as a small, asymptomatic, slow-growing dermal, subcutaneous, solitary lesion. More than 50% of these tumors are known to occur in the second decade of life and is often misdiagnosed clinically. Cytological features pose a diagnostic challenge although the histological features are very well delineated. This paper presents the cytological features in two cases outlining the importance of the clinicopathological features that need to be considered for an accurate diagnosis. Awareness of its varied cytologic features and clinical presentation can avoid misdiagnosis.