Cauda Equina Syndrome Caused by Pseudogout Involving the Lumbar Intervertebral Disc

Calcium pyrophosphate dihydrate (CPPD) deposition disease, also known as pseudogout, is a disease that causes inflammatory arthropathy in peripheral joints, however, symptomatic involvement of the intervertebral disc is uncommon. Herein, we describe a 59-yr-old patient who presented with cauda equina syndrome. Magnetic resonance imaging of the patient showed an epidural mass-like lesion at the disc space of L4-L5, which was compressing the thecal sac. Biopsy of the intervertebral disc and epidural mass-like lesion was determined to be CPPD deposits. We reviewed previously reported cases of pseudogout involving the lumbar intervertebral disc and discuss the pathogenesis and treatment of the disease.

Idiopathic Calcium Pyrophosphate Dihydrate (CPPD) Crystal Deposition Disease in a Young Male Patient: A Case Report

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is a disease of the elderly and extremely rare in young individuals. If young people develop CPPD crystal deposition disease, it may be associated with metabolic diseases such as hemochromatosis, hyperparathyroidism, hypophosphatasia, hypomagnesemia, Wilson's disease, hypothyroidism, gout, acromegaly, and X-linked hypophosphatemic rickets. Therefore, in young-onset polyarticular CPPD crystal deposition disease, investigation for predisposing metabolic conditions is warranted. We report a case of a young male patient with idiopathic CPPD crystal deposition disease, who did not have any evidences of metabolic diseases after thorough evaluations. As far as we know, this is the first report of a young male patient presented with idiopathic CPPD crystal deposition disease.

Condrocalcinosis articular / Articular chondrocalcinosis

El trabajo está basado en una muestra de 37 observaciones de condracalcinosis articular, seleccionadas de acuerdo a los criterios propuestos por Mac Carty. Se comienza por fijar la situación nosológica de la afección, estableciendo el concepto de enfermedades por depósito de microcristales. Se informa sobre la frecuencia de la condrocalcinosis articular en nuestro medio, su incidencia etaria y por sexo. Se analizan los diferentes patrones clínicos, se hace referencia a las imágenes radiológicas más frecuentes y se comentan los hallazgos de laboratorio. Se intenta una síntesis de los supuestos mecanismos fisiopatológicos planteados en la actualidad. Finalmente se destaca la existencia de formas inhabituales, especialmente de arteriopatías destructivas, y se esbozan directivas terapéuticas