Tissue immunostaining for factor XIIIa in dermal dendrocytes of pityriasis alba skin lesions

BACKGROUND: Pityriasis alba affects 1% of the world population and about 9.9% of the children in Brazil. However, its etiology remains uncertain. OBJECTIVE: The objective of the present study was to evaluate the immunoexpression of factor XIIIa in dermal dendrocytes of skin lesions of pityriasis alba. METHOD: Twenty patients with pityriasis alba and 20 patients with atopic dermatitis underwent biopsy. The dermal dendrocytes marked by factor XIIIa were counted by means of immunohistochemical analysis. RESULTS: The mean amount of dermal dendrocytes found in the patients with pityriasis alba was 2, whereas in the patients with atopic dermatitis it was 4, with a statistically significant difference between them. A cutoff point of 3 cells/square inch was established to differentiate pityriasis alba from atopic dermatitis, with 80% sensibility and 90% specificity. CONCLUSION: We believe that pityriasis alba and atopic dermatitis should be considered different clinical forms within the spectrum of atopic disease, in which sun radiation plays an important role by modulating the progression of the disease. .

Clinicopathological correlation of acquired hypopigmentary disorders.

Acquired hypopigmentary disorders comprise a significant group of disorders that affect Indians and Asians. The pigment disturbance in darker skin individuals can be very distressing to the patient and the family. These disorders cover a wide array of pathologies including infections, autoimmune processes, lymphoproliferative disorders, and sclerosing diseases. Histological diagnosis is particularly important because treatments for these diseases are varied and specific. This review will focus on histopathological diagnosis based on clinicopathological correlation for commonly encountered disorders such as leprosy, vitiligo, lichen sclerosus, pityriasis alba (PA), and pityriasis versicolor (PV). Atypical or uncommon clinical presentation of classic diseases such as hypopigmented mycosis fungoides (HMF) and hypopigmented sarcoidosis are also included.

Pityriasis amiantacea: clinical-dermatoscopic features and microscopy of hair tufts / Pitiríase amiantácea: aspectos clínicos e dermatoscópicos e microscopia dos tufos capilares

Pityriasis Amiantacea, also known as pseudotinea amiantacea, is a clinical syndrome which affects the scalp, having a reaction pattern reported to occur in several inflammatory dermatoses. The authors seek to establish the correlation between its clinical, dermoscopic and light microscopy features through the analysis of scale- encrusted hair tufts submitted to histological processing.

A pitiríase amiantácea, também chamada de pseudotínea amiantácea, é compreendida como uma síndrome clínica que acomete o couro cabeludo. Representa um padrão de reação a diversas dermatoses inflamatórias. Os autores procuram estabelecer a correlação entre características clínicas, dermatoscópicas e de microscopia ótica, através da análise do tufo de cabelos agregados pelas escamocrostas, submetido a processamento histológico.

Características clínico-epidemiológicas de pitiriasis alba en población de 6 a16 años en colegios nacionales del distrito de Manuel A. Mesones Muro, Lambayeque, Perú / Clinico-epidemiological fetaures of pityriasis alba in six- to sixteen- year old children in public schools in Manuel A. Mesones-Muro district Lambayeque, Perú

Objetivo: Describir las características clínico-epidemiológicas de la pitiriasis alba en la población de 6 a 16 años en los colegios nacionales del distrito de Mesones Muro, durante el periodo MarzoûJunio 2010. Material y método: Estudio descriptivo, prospectivo y transversal. Se usó una ficha de recolección de datos clínicos- epidemiológicos y una ficha de patologías asociadas y antecedentes dirigida a padres o apoderados. Se utilizó el programa Epidat v.3,1, para hallar el índice kappa que indicó la fiabilidad de concordancia entre evaluadores. Se utilizó toda la población de 6 a 16 años de colegios nacionales que pertenecen a la jurisdicción educativa del distrito. Se usó estadística descriptiva y analítica, con nivel de significancia p<0,05. Para el análisis se empleó el programa SPSS v.17,0. Resultados: De 548 estudiantes, 390(71,2%) presentaron pitiriasis alba. La edad promedio fue de 10,16±2,99 años; sexo masculino 52,6%; etapa adolescente 55,1%; localización más frecuente cara con 93,6%; lesiones múltiples en 92,3%; fototipo de piel más afectado IV con 61,8%; tiempo de enfermedad fue 5,34 ±6,85 años. Hay asociación entre pitiriasis alba con: patologías asociadas de acné; antecedentes personales de pitiriasis alba y atopía; y antecedentes familiares de pitiriasis alba y rinitis alérgica, encontrada con prueba chi2 y test exacto de Fisher con p<0,05. Conclusiones: La pitiriasis alba en Mesones Muro es un problema común. Las características epidemiológicas difieren de las encontradas en otras poblaciones, las características clínicas son similares a otras poblaciones. Se encontró asociación entre pitiriasis alba con patología asociada de acné; antecedentes personales de pitiriasis alba y atopía; mas no se encontró asociación de pitiriasis alba con sexo y edad por etapas de vida.

Objective: To describe clinical and epidemiological features of pityriasis alba in a 6- to 16- year old population of students from public schools in Mesones-Muro district, from March to June 2010. Materials and methods: This is a descriptive, prospective and crosssectional study. We collected clinical and epidemiological data, including associated diseases and clinical history in a specially designed form, which was administered to parents and/or guardians. We used the Epidat v. 3.1 software, in order to find the kappa index which indicated the reliability of agreement between raters. We surveyed the whole 6- to16- year old schoolchildren population from public schools belonging to this district educational jurisdiction. We used descriptive and analytical statistics, and significance was fixed with using a p <0.05 value. SPSSv.17.0. software was used for data analysis. Results: Out of 548 students assessed, 390 (71.2%) had pityriasis alba.Their average age was 10.16 ± 2.99 years, 52.6% were male, and 55.1% were adolescents. Facial lesions were found in 93.6%, multiple lesions in 92.3%, the skin phototype IV was most frequently affected (61.8%), and the time with the condition was 5.34 ± 6.85 years. We found an association between pityriasis alba and the following conditions: acne, a history of atopy, and a family history of pityriasis alba and allergic rhinitis, according to chi2 testing and FisherÆs exact test all with p <0.05. Conclusions: Pityriasis alba is a common problem in Mesones-Muro district. Its epidemiological characteristics differ from those found in other populations, but its clinical features are similar to those reported in other populations. There was an association between pityriasis alba with associated conditions, such as acne and a history of atopy, but there was no association between pityriasis alba and sex and life development stages.

Prevalência de pitiríase alba em pacientes com dermatite atópica na infância, de acordo com o fototipo / Prevalence of pityriasis alba in patients with atopic dermatitis in childhood according to the phototype

Fundamentos: A pitiríase alba (PA) é uma dermatose de etiologia não estabelecida, autolimitada, assintomática e de bom prognóstico. Caracteriza-se por lesões hipocrômicas, sendo um achado frequente da dermatite atópica. Objetivo: Estudar a prevalência da PA em crianças com dermatite atópica, de acordo com a cor da pele, classificada por fototipos. Metódos: Foram avaliados 62 prontuários de crianças com dermatite atópica, no período de março de 2008 a outubro de 2008. Estes pacientes foram classificados de acordo com o fototipo e avaliados quanto à presença ou não de ptiríase alba. Os dados obtidos foram submetidos à análise estatística. Resultados: Não houve prevalência da PA em relação ao sexo e a média da idade foi de 6,15 anos. A maioria dos pacientes (53,2%) apresentava lesões compatíveis com PA. Quanto ao fototipo, 62,9% eram fototipo 3, seguido por fototipo 4 (22,5%). Houve maior prevalência de PA nos fototipos 4 e 5 (82%) e a análise estatística demonstrou que esses pacientes têm seis vezes mais chance de manifestarem PA do que as crianças com fototipos 2 e 3. A associação entre o fototipo e a manifestação de PA foi estatisticamente significativa (p=0,0047). Todas as crianças avaliadas tinham xerose de leve a moderada. Conclusão: A pitiríase alba guarda importante relação com o fototipo do paciente atópico, independente da gravidade do quadro ou da presença de xerose.

Dermatoses do pavilhäo auricular / External ear dermatosis

Apresentamos uma atualizaçäo sobre as dermatoses que ocorrem no pavilhäo auricular. Propomos uma classificaçäo em sete grupos e realizamos uma sucinta descriçäo clínica de cada uma das 84 entidades catalogadas, de forma didática, com a finalidade de auxiliar o médico, sobretudo o clínico geral, o dermatologista e o otorrinolaringologista, no diagnóstico de tais patologias.

Clinicopathologic study on pityriasis alba

Pityriasis alba (PA) is a relatively common skin disorder usually seen in children and young adults characterized by the presence of superficial hypopigmented macules. A clinicopathologic study on pityriasis alba was undertaken which showed an increased ocurrence of the disease in preadolescent children with

Pityriasis rosea: a serial estimation of the serum IgG, IgM, IgA and C3 during the course of the disease

Pityriasis rosea is a relatively common skin disease throughout the world. Its etiology remained a mystery and obscure since it was described. A possible virus was suspected. The result of follow up estimation of Ig showed that the serum level of IgM underwent significant increases, which substantiates a possible viral etiology

Parapsoriasis en la infancia / Parapsoriasis in the infancy

Se presenta 8 pacientes con pitiriasis liquenoide de la infancia, correspondiendo 3 de ellos a la forma clásica, uno asociando pitiriasis liquenoide aguda de mucha-Habermann y forma clásica, otro asociando pitiriasis liquenoide aguda, forma clásica y forma leucodérmica, dos leucodérmica de la infancia y el restante asociando las variedades leucodérmica y purpúrica

Pitiriasis liquenoide y variceliforme aguda / Acute lichenoides and varioliforms pityriasis

La pitiriasis liquenoide y variceliforme aguda es una dermatosis benigna, polimorfa, de etiología desconocida. Con frecuencia surge como un episodio agudo inicial de pápulas, elementos variceliformes y necróticos generalizados. Puede presentarse como tal en sus brotes recidivantes o en el curso evolutivo de una parapsoriasis en gotas. Se comunica el caso de una paciente de 22 años con diagnóstico de P.L.E.V.A., lo que motivó a efectuar una revisión del tema. Se utilizó la eritromicina, por ser una medicación menos agresiva, para una patología de evolución incierta y pronóstico favorable

Pityriasis lichenoides et varioliformis acuta (doença de Mucha-habermann) / Pityriasis lichenoides et varioloformis acuta (Mucha-habermann disease)

Os autores apresentam um caso recentemente observado de Pityriasis lichenoides et varioliformis acuta (PLEVA) que apresentou involuçao espontânea e fazem sucinta revisao dos aspectos terapêuticos da dermatose.