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Braz. j. infect. dis ; 12(6): 469-471, Dec. 2008. ilus
Artigo em Inglês | LILACS | ID: lil-507443

RESUMO

The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety "Vitória de Verão" genetically modified.


Assuntos
Antígenos de Superfície da Hepatite B/genética , Vacinas contra Hepatite B/genética , Lactuca/genética , Plantas Geneticamente Modificadas/genética , DNA Recombinante , Lactuca/imunologia , Reguladores de Crescimento de Plantas , Plantas Geneticamente Modificadas/imunologia , Plântula/genética , Plântula/imunologia , Vacinas de Plantas Comestíveis
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