Morphometry of choroid plexus in hydrocephalic guineapigs.

To study the quantitative changes if any, in different components of the choroid plexus in association with hydrocephalus, young guineapigs were made hydrocephalic by intracisternal injection of kaolin (125 mg/ml). Choroid plexuses of these animals and controls were embedded in durcupan. Using morphometric methods volume and surface area of the choroidal epithelium and interstitial tissue were estimated from 2 microns thick sections. No significant change was observed in the volume of interstitial tissue and surface area of the luminal part of the blood vessels in the hydrocephalic guineapigs. But the volume and surface area of the choroidal epithelium of the hydrocephalic guineapigs showed significant decrease as compared to that of control group, which may be interpreted as decreased activity of the choroidal cells and in turn decreased secretion of CSF in hydrocephalus. This may be secondary to the increased intraventricular pressure associated with hydrocephalus.

Two cases of anterior choroidal artery territory infarction

Occlusion of the anterior choroidal artery (AChA) can cause infarction in the posterior limb of the internal capsule. Infarction is less frequently observed in the thalamus, midbrain, temporal lobe, and lateral geniculate body (LGB) territories of the AChA. The most common clinical finding is hemiparesis. Hemianesthesia may be severe at onset but is usually transient. Homonymous hemianopia, upper-quadrant anopia, or upper- and lower-quadrant sector anopia can be present. Occasionally these patients are reported to have transient abnormalities of higher cortical function. The most common stroke mechanism is known to be small-vessel occlusive disease, predominantly found in hypertensive and diabetic patients. Vasospasm due to ruptured aneurysm or intraoperative mechanical manipulation, and cardiac origin the AChA territory. The infarct lesion is usually recognized and diagnosed by computed tomography. The best treatment is still unknown.