RESUMO
A case of recurrent sino-naso-orbital fungal infection due to Pseudallescheria boydii described in a 28 yrs. old man, who appeared immunocompetent, and was found negative for HIV I and II by ELISA tested on two occasions. The fungal culture was negative. It is very essential to identify P boydii as Miconazole is the only antifungal drug of choice for this fungus. The pathologist plays an important role in identifying this fungus when fungal culture fails to yield the growth. The pathologist has to look for clinching clues such as "intercalary conidia" and "chlamydoconidia" to distinguish P boydii from Aspergillus.
Assuntos
Adulto , Antifúngicos/uso terapêutico , Doença Crônica , Humanos , Imunocompetência , Masculino , Miconazol/uso terapêutico , Micoses/diagnóstico , Doenças Orbitárias/diagnóstico , Pseudallescheria/efeitos dos fármacos , Sinusite/diagnósticoRESUMO
Paciente de sexo femenino, 48 años, sin antecedentes clínicos de importancia presenta obstrucción nasal, rinorrea y poliposis. La tomografía axial computadorizada revela masa heterogénea en cavidad maxilar y paranasal derechas, fosa nasal con desviación del tabique y erosión ósea. Se efectúa sinusotomía maxilar derecha y del material se aísla pseudallescheria boydii. Recibe tratamiento con anfotericina B 975 mg hasta tipificación del agente etiológico; continúa con itraconazol 200 mg/día hasta la fecha (9 meses) sin recidivas