Rotura del septum interventricular post infarto agudo al miocardio: una complicación potencialmente letal Revisión de la literatura a propósito de un caso clínico / Ventricular septal rupture after acute myocardial infarction: a potentially lethal complication Case report and literature review

Rupture of the ventricular septum with the appearance of an interventricular communication is an infrequent and life-threatening mechanical complication after acute myocardial infarction. The advent of coronary reperfusion therapies has reduced the incidence of this complication, but mortality remains high. The clinical presentation varies from mild compromise with exertional dyspnea to severe compromise with cardiogenic shock. In this pathology, early diagnosis is fundamental and surgical repair is the treatment of choice. In this article we report an interesting clinical case about a 77-year-old woman who was belatedly referred to our hospital and diagnosed with postinfarction rupture of the ventricular septum with an unfortunately fatal evolution. Relevance of this case lies in its atypical clinical presentation which led to a delay in diagnosis and a missed opportunity for early reperfusion therapy. An updated literature review about rupture of the ventricular septum complicating acute myocardial infarction was carried out.

Spontaneous perforation and dissection of the sinus of Valsalva and interventricular septum with intracardiac thrombus in a patient with Behcet's disease

No abstract available.

Ruptura de parede septal e corda tendínea de valva tricúspide após infarto audo do miocárdio / Ventricular septal perforation and rupture of the chordae tendineae of the tricuspid valve after acute myocardial infarction

Ruptura de parede septal (RPS) no infarto agudo do miocárdio (IAM) é uma complicação com alta mortalidade, com incidência de 0,2% na era de reperfusão miocárdica. Relata-se um caso de paciente com IAM associado à RPS, e possível rotura de cordas tendinosas da valva tricúspide.

Postinfarction ventricular septal perforation (VSP) is high-mortality complication with an incedence of 0,2%. This paper presents a case report on a patient presenting VSP in association with a possible rupture of the chordae tendineae of the tricuspide valve.

Características clínicas, modalidades de tratamiento y mortalidad en la ruptura del septum interventricular posinfarto / Clinical characteristics and treatment of ventricular septum rupture after acute myocardial infarction

Objetivo: Conocer las características, estrategia de tratamiento y mortalidad en pacientes con infarto agudo al miocardio y ruptura del septum interventricular posinfarto. Métodos: Se incluyeron 40 pacientes atendidos en un periodo de ocho años por infarto agudo al miocardio complicado con ruptura del septum interventricular posinfarto. Se utilizó ecocardiograma para confirmar la ruptura del septum interventricular posinfarto. Se evaluaron las características clínicas, el tipo de tratamiento y la mortalidad hospitalaria. Las variables se compararon con prueba U de Mann-Withney o prueba exacta de Fisher. Resultados: Edad 64 años (56 a 73), 67% hombres, 53% diabetes, 43% hipertensión, 40% tabaquismo. Los tratamientos fueron: conservador 45%, quirúrgico 38% o dispositivo Amplatzer 17%. La mortalidad general fue de 65%, con manejo conservador 54%, con cirugía 35% y con Amplatzer 12% (p = 0.02), y estuvo asociada a menor tiempo entre infarto agudo al miocardio y ruptura del septum interventricular posinfarto (p <0.001) y menor tiempo entre ruptura del septum interventricular posinfarto y tratamiento de cierre (p <0.001). Todos los pacientes con Killip Kimbal III o IV murieron. Conclusiones: Hasta el momento no existe una estrategia de manejo en la ruptura del septum interventricular posinfarto que demuestre ventajas sobre las demás. El único marcador de buen pronóstico podría ser el mayor tiempo entre la ruptura y el tratamiento de cierre. Es probable que la indicación de manejo de las guías internacionales no aplique para todos los pacientes y estos deban estratificarse de acuerdo a su estado hemodinámico.

Objective: To identify the characteristics, management strategy and mortality of patients with acute myocardial infarction (AMI) and rupture of ventricular septum (RVS). Methods: The study included 40 patients admitted during a period of 8 years, due to AMI complicated with RVS. RVS was confirmed by echocardiogram. The clinical characteristics, type of treatment and hospital mortality were evaluated. Variables were compared by Mann-Withney U tests or Fisher exact test. Results: Patients were 64 years old (56 - 73), 67% men, 53% diabetes mellitus, 43% hypertension, 40% smokers. Treatments were medical (45%), surgical (38%) or Amplatzer (17%). Overall mortality was 65%, in conservative group was 45%, in surgery group 38%, and Amplatzer group 17% (p = 0.02), it was associated to shorter time between AMI and RVS (p <0.001) and shorter time between and treatment (p <0.001). All patients with Killipp Kimbal III or IV died. Conclusions: Currently there is no management strategy in RSV with demonstrated advantage over other strategies. The only marker with good prognosis could be a long time between rupture and treatment. It is likely that the indication of management of International guidelines does not apply to all patients and these should be stratified according to their hemodynamic status.

Successful treatment of early postinfarction massive ventricular septal rupture and cardiogenic shock

A 65 years old woman presented to the ER with vomiting and severe retro-sternal chest pain for twelve hours. She was extremely dyspneic with a respiratory rate of 32/min, heart rate of 120/min, blood pressure of 70/50 mmHg and 02 saturations of 91% on 15 liters by face mask. She had bilateral crepitations upto mid lung zones bilaterally and had pan systolic murmur and had cool extremities with no pedal pulses. ECG showed massive anterior ST elevation myocardial infarction. An emergent echocardiography showed dilated right ventricle, and a large ventricular septal rupture anteriorly with severely reduced LV function. Patient was intubated, taken to the cardiac catheterization lab. An IABP was placed and on angiography large ventricular septal rupture was identified along with complete LAD occlusion. Median sternotomy was performed and patient was placed on cardiopulmonary bypass. The anterior infracted portion was excised and large anterior VSD was identified. The edges were debrided and then a large 7.5 cm defect in the anterior interventricular septum was identified. A Dacron patch was sewn along the edges of the VSD with interrupted plegeteted ethibond sutures and then the free wall of the LV and RV were brought together with plegeted prolene sutures; thus sandwitching the patch and closing the ventricular free wall also. LAD was grafted with a vein graft. IABP was removed after 48 hours and the patient was extubated. The rest of the hospital stay was unremarkable and patient was discharged home in 10 days

Ruptura do septo interventricular após trauma torácico fechado / Ventricular septal rupture following blunt chest trauma

Relatamos a seguir um caso de ruptura do septo interventricular após trauma torácico automobilístico com evolução relativamente benigna a despeito da extensão da lesão anatômica.

We report a case of ventricular septal rupture following chest trauma resulting from a car accident. The outcome was relatively favorable despite the extension of the anatomic lesion.

Perforation of interventricular septum in acute myocardial infarction.

Eight cases of ruptured interventricular septum associated with myocardial infarction were diagnosed at Siriraj Hospital between 1985-1995. Clinical congestive heart failure and holosystolic murmur were found in all. Diagnosis was confirmed by echocardiogram and right heart catheterization in all patients. Two patients died from congestive heart failure preoperatively and the third case died from organ failure and sepsis postoperatively. Another five cases underwent successful ventricular septal defect closure and coronary artery bypass with good results.