Nephrotic syndrome following Schistosoma mansoni

A young Sudanese female presented with features of generalized edema for the last three years. Examination showed anasarca, hepatomegaly and anemia. Investigations confirmed the presence of Nephrotic syndrome with normal renal function. It also showed iron deficiency anemia and leukamoid reaction, hypereosinophilia. Causes for hypereosinophilia were excluded. Renal biopsy showed the diagnosis of amyloidosis. Stool by concentration method diagnosed. Schistosoma mansoni as possible explanation for all the, manifestations. Leucocytosis, hypereosinophilia responded to steroids and antihelminthic therapy however the patient glomerulopathy progressed to end stage and the patient was put on regular renal replacement therapy