Research advances on signaling pathways affecting sweat gland development and their involvement in the reconstitution of sweat adenoid cells in vitro / 中华烧伤杂志

The damage of sweat glands in patients with extensive deep burns results in the loss of thermoregulation, which seriously affects the quality of life of patients. At present, there are many researches on the repair of sweat gland function, but the mechanism of human sweat gland development has not been fully clarified. More and more studies have shown that the cascaded pathways of Wnt/β-catenin, ecto- dysplasin A/ectodysplasin A receptor/nuclear factor-κB, sonic hedgehog, and forkhead box transcription factor jointly affect the development of sweat glands, and it has been reported that the cascaded signaling pathways can be used to achieve the reconstruction of sweat adenoid cells in vitro. This article reviews the signaling pathways that affect the development of sweat glands and their involvement in the reconstruction of sweat adenoid cells in vitro.

"Suando a camisa" em academias de ginástica do Rio de Janeiro: um estudo etnográfico / "Sweating the shirt" in fitness centers of Rio de Janeiro: an ethnographic study

Resumo As secreções humanas podem indicar como os grupos sociais compreendem múltiplas formas de usos do corpo. Assim, o objetivo deste trabalho foi analisar como o suor pode ser concebido pelos alunos em academias de ginástica. Durante um ano, foi realizada pesquisa etnográfica comparativa em academias de pequeno e grande porte, respectivamente, inseridas em um bairro popular e nobre do Rio de Janeiro. Foi possível concluir que enquanto na academia de pequeno porte havia certa positividade atribuída ao suor devido à sociabilização e à noção de sucesso na performance durante as práticas corporais e cotidiano laboral, na academia de grande porte o mesmo tendia a ser visto com repulsa, limitando os encontros face a face e os esforços físicos extenuantes.

Abstract Human secretions can indicate how some social groups understand the large number of possibilities to use the body. This study aimed to analyze how sweat can be perceived by the users when they are in a fitness center. An ethnography research was conducted during one year in Rio de Janeiro city, comparing a small and a large fitness center, the former located in a popular neighborhood and the latter in a noble neighborhood. Therefore, as long as sweat was noticed in a positive way in the small fitness center and related to performance improvements, in the other fitness center sweat was conceived as something repulsive, limiting the meeting between users and the exhaustive exercises.

Fibrosis quística: diagnóstico tardío en el adulto presentación de caso / Delayed diagnosis of the cystic fibrosis in adulthood: a case report

Se presenta el caso de un paciente blanco de 47 años con cuadros respiratorios a repetición que cedían con tratamiento sintomático o con el uso de antibióticos por vía oral desde la infancia. A los 39 años de edad, comenzó con agudizaciones más frecuentes que requirieron tratamientos con antibióticos e ingresos en varios hospitales de Ciudad de La Habana, y se le diagnosticó Bronquiectasias diseminadas bilaterales e infectadas con Pseudomonas Aeruginosas, secundarias a una posible Tuberculosis adquirida en la antigua URSS a los 21 años. La falta de lesiones hacia los vértices pulmonares en la radiografía de tórax y el hecho de no haber nunca tenido hijos despertó la sospecha clínica de Fibrosis Quística, la cual fue confirmada por los estudios realizados posteriormente. Nuestro propósito al presentar este caso es alertar que esta enfermedad ha dejado de ser una patología exclusiva de Pediatría y que debe sospecharse ante un cuadro florido de bronquiectasias(AU)

The case of a 47 years old white patient, that presented repeated respiratory symptoms that only improve using symptomatic treatment or oral antibiotics. In 2000 when, he was 39 years old their symptoms increased and he required antibiotic intensive treatment and incomes at several hospital in Havana. After that, he was diagnosed with multiple bronchiectasis spread bilateral and infected Pseudomona Auriginosa, that could brings about, TB acquired at URSS when he was 21 years old. In 2008 because of the absence of lesions toward pulmonary apex in the Rx and the fact he couldn't have children aroused the clinical suspicion of Cystic Fibrosis and it was later confirmed by the accomplished studies. Our purpose to present this case is to alert and prevent that this disease has stopped being Pediatric's exclusive pathology and it should be taking into account when there is a complete picture of a multiple spread bronchiectasis(AU)

Asombroso: dos pacientes que sudan sangre por la piel / Amazing: two patients that sweat blood through their skin

Antecedentes: Jesús, en el huerto de Getsemaní, poco antes de entrar en su pasión, según relatan los evangelistas "su sudor se convirtió en gruesas gotas de sangre que caían hasta el suelo. Además de este caso, solamente dos casos mas hemos encontrado reportados en la literatura médica mundial. Materiales: Paciente femenina de 22 años de edad, raza blanca, natural y residente en el paraje Soledad, Moca, Prov. Espaillat, R.D. y su hijo varón de tres años de edad, en quienes se reportan sudoración de sangre en mas de una oportunidad, Conclusión: se trata sin lugar a dudas de casos de hematohidrosis, algo excepcional reportado, posiblemente por primera vez en la República Dominicana

Sweat osmolality in some of the congenital diseases.

Sweat osmolality pattern was studied in Indian sub population of both controls and patients with congenital diseases. A Normal range for sweat osmolality was established for different age groups and sex (100-150 mmols/kg) and compared with the patients, who were clinically diagnosed as cystic fibrosis, Down's syndrome and mentally retarded cases. The study has revealed that sweat osmolality varies according to age and sex in normal population implying the effect of endocrinological changes associated with the onset of puberty. Further, it was also observed that an elevated sweat osmolality is not unique to cystic fibrosis alone, but seen among the Down's syndrome and some of the mentally retarded cases where in the etiology is traced to the inborn errors of metabolism.

Effect of glucose electrolyte ingestion on physiological changes due to severe heat stress.

Severe heat stress experienced by aircrew during summer months can cause deterioration in performance. Acute heat stress can also lead to dehydration and loss of electrolytes. Previous studies emphasised the need of K+ replacement. This study was carried out to determine the effect of glucose electrolyte ingestion (ELECTRAL) on thermal strain parameters. Ten healthy male subjects in the age group of 19-43 years were exposed to an acute thermal environment of 50 degrees C Tdb with relative humidity of 30% for 40 min. twice each day on two different days with an interval of one hour in between the exposures. At the beginning of rest period electrolyte solution was ingested during electrolyte trials and water under control trials. Physiological parameters of Tsk, T or, HR and electrolyte concentration of Na+ and K+ in sweat did not show any significant difference in both the trials. Sweat loss was significantly higher during electrolyte trials.