Actualización en lupus neuro-psiquiátrico con énfasis en déficit cognitivo / An update on neuropsychiatric lupus with emphasis in cognitive dysfunction

Background: physically and psychologically. We review herein the nomenclature and case definitions for neuropsychiatric lupus syndromes proposed by the American College of Rheumatology in 1999. We emphasize cognitive dysfunction and discuss etiological hypotheses, especially those related to the presence of antineuronal autoantibodies.