RESUMO
Serum alpha 1-antitrypsin, alpha 1-antichymotrypsin and alpha 2-macroglobulin increased significantly in patients suffering from liver diseases: hepatoma, amoebic liver abscess, hepatitis, hepatic cirrhosis, cholangiocarcinoma, carcinoma of the head of pancreas including liver fluke infection (opisthorchiasis). Marked increase of alpha 1-antitrypsin and alpha 1-antichymotrypsin were found in cholangiocarcinoma, carcinoma of the head of pancreas, amoebic liver abscess, hepatic cirrhosis and hepatoma. alpha 2-macroglobulin increased markedly in hepatic cirrhosis. The concentrations of protease inhibitors found in opisthorchiasis were only moderately elevated.
Assuntos
Adenoma de Ducto Biliar/sangue , Adulto , Neoplasias dos Ductos Biliares/sangue , Carcinoma Hepatocelular/sangue , Feminino , Humanos , Hepatopatias/sangue , Neoplasias Hepáticas/sangue , Masculino , Pessoa de Meia-Idade , Opistorquíase/sangue , Inibidores de Proteases/sangue , alfa 1-Antiquimotripsina/análise , alfa 1-Antitripsina/análise , alfa-Macroglobulinas/análiseRESUMO
The infrared spectrum of native black-eyed pea trypsin and chymotrypsin inhibitor (BTCI) in solid film was measured from 550 to 1750 cm-1 and amide I-III, and V regions have been analyzed. By comparison between the observed bands with the modes calculated for several structures (available inthe literature), the occurrence in BTCI of unordered, antipatallel ß-sheet, and ß-turn structures is suggested