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Indian J Med Sci ; 2011 Aug; 65(8) 317-320
Artigo em Inglês | IMSEAR | ID: sea-145623

RESUMO

The world has seen the emergence of many micro-organisms in the recent past, which can curb human population with their newly built genetic make-up. The latest addition to this list of panic creating organisms is, bacteria encoding the gene for New Delhi metallo-beta-lactamase (NDM-1). NDM-1 is an enzyme that can hydrolyze and inactivate carbapenems, which are used as a last resort for the treatment of multi-resistant bacterial infections. Names of these bacteria were not found in the medical literature before December 2009, because of which it can take the credit of becoming a powerful emerging bacteria, which are difficult to treat. Besides Escherichia coli and Klebsiella pneumoniae, other bacterial strains have also expressed the gene for NDM-1, which are detected in many countries.


Assuntos
Carbapenêmicos/metabolismo , Farmacorresistência Bacteriana Múltipla/efeitos dos fármacos , Farmacorresistência Bacteriana Múltipla/genética , Escherichia coli/efeitos dos fármacos , Índia , Klebsiella pneumoniae/efeitos dos fármacos , beta-Lactamas/biossíntese , beta-Lactamas/genética , Resistência beta-Lactâmica/genética , beta-Lactamases/biossíntese , beta-Lactamases/genética
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